SESN1 (NM_014454) Human 3' UTR Clone

Specifications

Product Data
Product Name	SESN1 (NM_014454) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	PA26; SEST1
ACCN	NM_014454
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC212558 3’UTR clone of NM_014454 The sequence shown below is from the reference sequence of NM_014454. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTGAGAGCCATTACCCGCTATATGACCTGATGCCTTTCCTTCATTAAAGATGATTCTGGAATGATCAGC AGATATAGTCTACAAGGGGGAAGGTACTAAGCCCCAGGACCAATGGTAGACAAAATAATTCAGAAATCC ATTGTGCCATGATTCCTTTAGTTTCTGCTATTTTTCTGTGGAAAACCACTGCTGGCACAAGCAGTGACT GTTTGGCAGCTTCAAGTTTAGAGCTGTGAAGACAGGCTGCCATTCACAGTATTTTGCTTTTTGACAGTA CAAGATGCTGTGTAACTGTTTTAATACAGCAAATAGTAACTCTCCAAATCCTGTTGCTTTTATGTTAAA TAAGATAACAAGAATTGGAGCATGCAAAGAATGGGACTTGGATAATGACTTAAGCTTTATATGTAAAGA ATTTTAGAAGATCTTGGTGCTGCTATTCCTGCTGGAGGAATGAATAGATGGCTGTTTCAGTTAAGCTAT TAGTAATAAAAGTGAACATTGCTACTATCTGAGCCTACATACATAACTTGTGTGATTTCAAATTAAACT TGCATTATGTGTTAATTTTCTTGCATCTAAAAAAGCATAGAATTCCTACTCACACAGCTCAGCAACAAC CATTTTGATGGTAACAGTTAATTTCTTTCATTAGTTTTTTAAATTCAGGGTTCTGGATATTAAATTAAA ATGGCATTCTTAAAGATTTTCTTCAAAAAGCAATCCTAAATGAAAGTGTGTAAATTATAAGAAGCTGGC GATCTTTTGATATGCTGTTTCACAGGATCCTGACACTGGAGGGCAGCTGTCTTGTGCATTACTTGTGTT TCCAGCACCAAAGTTGTGGGACATGTTGCTGTAGACTGCTGCGCAGTCCTGGGTGCATTCAGTCTCTCT GCCTCTGCCTGCCTCCTGGTCCCCACTTTAAAGGCTGTGCAGCTCCTTAAATAATAAAGCTGGAAAATA TTTTTAGTCGGGTTATCAAATTTGATTTACAAAAACGCTAACTTTGTTTGAAATGCAAACAGGTTTGAA AATATGTATTAAGTACTTTGTATTCTGGAAGCGTGAATTGCTTTTGAAGTCTGTCAGTATTACTGGTAT TTTTAAATAAAGAAGAATTTTTCTCCAATTTTATTTGCTGTCTCAATCTCTTAAAAAATCATGACTTCA CTATTAGTAATAATTTTGAGTTTCTATCTACTTTCATAAGCCAAGTACATTCACACTTAAATGGCAAAA CAACACTTGAAGCCATTTTGAAACATACAAAGAGGAGTGGACTTTCTTTAGAATCTTATCTGAGACCAT TTTTATCTTGGAAATGACTGGTATGGCCCTATGCCTGCTCTCTTTTCAACTGTTTTAGAGTTCCAATAG AATTTTAAGAATTACTAAAAAGAAGGATTCATTAGGGAGAGACTACAGAACAAAAAATGACACTCATCA GACAAGTAGAAATAGCTCTAAGTTTAACTGAAGCTGTTGTGATGATAACTCTGTTAGTTACTCCTCAAA ACATTTATTGAGCTCAATCTAGTGCCTGCCTACAAATGTATGGGGTAGTGTGGAAGTAGGGGTTGGGAA GGATCAATTTTGAACAGAGGTGGTACCTGTCCTCAAGGATATTTACTCTCATGAGAAGACAAGACTATA ACCTTAGCTAGGAATAGAGTATTATTATCTTCAATATGTTTTATATTTAAAGAAACTTACTTATAAGTG CATTACTCATTGAATATGCATCATGCCTTTGTCCTCTTCTGCCTGCTGCTGAGTTCTCTCACCAGAGCA ATACAATTGAACCCAAGAAGATAGTTAAAATTTTACTTATCCCATTTCTGCTCTTTGTTCCTCCTCTTG AAAATACAAAATTTCTAGTAGAGATTCTAATCAGCAGTAGAGTGATCACAAAACAAGATCAACTAGAAT GCATTTAGTCCACTGGAACTTATAATCACTTAGAAATTGAAATCAAAATTTTAATGAGTTAAAAAATA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_014454.3
Synonyms	PA26; SEST1
Summary	This gene encodes a member of the sestrin family. Sestrins are induced by the p53 tumor suppressor protein and play a role in the cellular response to DNA damage and oxidative stress. The encoded protein mediates p53 inhibition of cell growth by activating AMP-activated protein kinase, which results in the inhibition of the mammalian target of rapamycin protein. The encoded protein also plays a critical role in antioxidant defense by regenerating overoxidized peroxiredoxins, and the expression of this gene is a potential marker for exposure to radiation. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Dec 2010]
Locus ID	27244
MW	76.3

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.