FOXP2 (NM_148899) Human 3' UTR Clone

Specifications

Product Data
Product Name	FOXP2 (NM_148899) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CAGH44; SPCH1; TNRC10
ACCN	NM_148899
Insert Size	131 bp
Sequence Data	Insert Sequence (showhide) >SC212501 3’UTR clone of NM_148899 The sequence shown below is from the reference sequence of NM_148899. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGTGCATATTGCTTTATAAACAGTAAATAGCTCTACCAATGTAACAGACTAAGAAAATGAACAATTTAG TGACAGTTAGAAAACAATGAGTGTGATGAAAAATACGGCAATAAAATGAAAGTAAAATGTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_148899.3
Synonyms	CAGH44; SPCH1; TNRC10
Summary	This gene encodes a member of the forkhead/winged-helix (FOX) family of transcription factors. It is expressed in fetal and adult brain as well as in several other organs such as the lung and gut. The protein product contains a FOX DNA-binding domain and a large polyglutamine tract and is an evolutionarily conserved transcription factor, which may bind directly to approximately 300 to 400 gene promoters in the human genome to regulate the expression of a variety of genes. This gene is required for proper development of speech and language regions of the brain during embryogenesis, and may be involved in a variety of biological pathways and cascades that may ultimately influence language development. Mutations in this gene cause speech-language disorder 1 (SPCH1), also known as autosomal dominant speech and language disorder with orofacial dyspraxia. Multiple alternative transcripts encoding different isoforms have been identified in this gene.[provided by RefSeq, Feb 2010]
Locus ID	93986
MW	5.2

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