CD153 (TNFSF8) (NM_001244) Human 3' UTR Clone

Specifications

Product Data
Product Name	CD153 (TNFSF8) (NM_001244) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CD30L; CD30LG; CD153; TNLG3A
ACCN	NM_001244
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC212335 3’UTR clone of NM_001244 The sequence shown below is from the reference sequence of NM_001244. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCCATCTTCTTATACAGTAATTCAGACTGAACAGTTTCTCTTGGCCTTCAGGAAGAAAGCGCCTCTCTA CCATACAGTATTTCATCCCTCCAAACACTTGGGCAAAAAGAAAACTTTAGACCAAGACAAACTACACAG GGTATTAAATAGTATACTTCTCCTTCTGTCTCTTGGAAAGATACAGCTCCAGGGTTAAAAAGAGAGTTT TTAGTGAAGTATCTTTCAGATAGCAGGCAGGGAAGCAATGTAGTGTGGTGGGCAGAGCCCCACACAGAA TCAGAAGGGATGAATGGATGTCCCAGCCCAACCTCTAATTCACTGTATGGTCTTGATCTATTTCTTCTG TTTTGAGAGCCTCCAGTTAAAATGGGGCTCCAGTACCAGAGCAGCTAGCAACTCTGCCCTAATGGGAAA TGAAGGGGAGCTGGGTGTGAGTGTTTACACTGTGCCCTTCACGGGATACTTCTTTTATCTGCAGATGGC CTAATACTTAGTTGTCCAAGTCGCGATCAAGGACTCTCTCACACAGGAAACTTCCCTATACTGGCAGAT ACACTTGTGACTGAACCATGCCCAGTTTATGCCTGTCTGACTGTCACTCTGGCACTAGGAGGCTGATCT TGTACTCCATATGACCCCACCCCTAGGAACCCCCAGGGAAAACCAGGCTGGGACAGCCCCCTGTTCCTG AGATGGAAAGCACAAATTTAATACACCACCACAATGGAAAACAAGTTCAAAGACTTTTACTTACAGATC CTGGACAGAAAGGGCATAATGAGTCTGAAGGGCAGTCCTCCTTCTCTAGGTTACATGAGGCAGGAATAA GAAGTCAGACAGAGACAGCAAGACAGTTAACAATGTAGGTAAAGAAATAGGGTGTGGTCACTCTCAATT CACTGGCAAATGCCTGAATGGTCTGTCTGAAGGAAGCAACAGAGAAGTGGGGAATCCAGTCTGCTAGGC AGGAAAGATGCCTCTAAGTTCTTGTCTCTGGCCAGAGGTGTGGTATAGAACCAGAAACCCATATCAAGG GTGACTAAGCCCGGCTTCTGGTATGAGAAATTAAACTTGTATACAAAATGGTTGCCAAGGCAACATAAA ATTATAAGAATTCACTATACCTTCCCCTCCCTGGAACTCAGGATCCAAGTCTAGAAAATGAAAGGACTG GGTTTGAATTGCTTCAAAACCTCTTCCATCTCAGAAGACCAGACCCTGGGAACTGAGATTCCAGACACA ATTTTGGAAGCTCTCCAACCAAAATAAGGCCCCCCTACCCCAGTATATAATTGAAGACACTAGTAACAC CTGACTGCATCTCATCTCAGCAGAGCCAGAATATGGGGACAAGGTTCAGGGTGCCCTGCTGAATGGTGT GAACAGCAGGATCTCAAGGATGTAATGGAAAGAACTACCACACTGACCATCCAGAATCTAAGAGACCAT CTGGGTGTTTGGGAAACCATCTGACGAGGCCTGACTCTATTCCAGTTAGATTGACAATAATTGAGCAGC AGGCATTTTTCATTTCTGGTCAGGAAAGCATTGTGCCTTTAGCAAACAATCAGTGTGCAACAGTGATGT GGTCATCTAGCCAGGGAATGGCTGCTCCATCCCCTGCATAATATATTCCTGCTTCAAACACCTCTCAGA AAACCAGTTCCGCGAGGGTTTTTATATCCCCACAAAGTTGTTGAGAGACAATGATGACCCTGGAAGTGG GGAGGAGGACTTCTGAGAAACAGCAACCTCTCTCCTGATTGGGGTAGCCATGAGATTTCTCTAGCTATA TCCAACTTGGCATCTGTACATCATCTTTGGAGGAACATCTTATTTGTGGAAGGACCTTGACAAGCCGTT TGAGATGGAATGTAGGCCCTGATGTTATGCTTCAGTAAAAAAAGATGGAAGCTTCCCTGCTATACCAAA ACATGGAGCAAAATTTGCATTTTTCTCAAGAAGGAGAGAAAAGGAGTAGGACTCCAGCAAAGTTTGTC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001244.4
Synonyms	CD30L; CD30LG; CD153; TNLG3A
Summary	The protein encoded by this gene is a cytokine that belongs to the tumor necrosis factor (TNF) ligand family. This cytokine is a ligand for TNFRSF8/CD30, which is a cell surface antigen and a marker for Hodgkin lymphoma and related hematologic malignancies. The engagement of this cytokine expressed on B cell surface plays an inhibitory role in modulating Ig class switch. This cytokine was shown to enhance cell proliferation of some lymphoma cell lines, while to induce cell death and reduce cell proliferation of other lymphoma cell lines. The pleiotropic biologic activities of this cytokine on different CD30+ lymphoma cell lines may play a pathophysiologic role in Hodgkin's and some non-Hodgkin's lymphomas. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011]
Locus ID	944
MW	75.8

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