RAP1GAP (NM_001145657) Human 3' UTR Clone

Specifications

Product Data
Product Name	RAP1GAP (NM_001145657) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	RAP1GA1; RAP1GAP1; RAP1GAPII; RAPGAP
ACCN	NM_001145657
Insert Size	1108 bp
Sequence Data	Insert Sequence (showhide) >SC212316 3’UTR clone of NM_001145657 The sequence shown below is from the reference sequence of NM_001145657. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAGCAGCACATGCCCCAGCTGGGCTGTTAGCCGGGCCACCCCCTCTGAAGGTGAAACTGAGCAGATGAG GCCACAGAAGCACAAGGGGAAGGTGCCGTGTCAAGCCCAGGCAGACGAGACCTCTGCCCTGAAGACCAA CACCAGCCCGTGGGCTGCCCCCTGCCTCCCCACCCTCCCCATGGCCCACCCATCTGGGCTGTCTCTGCA GGGCAGAGCCGTCCAGACCTGGGATCAGGGAAGCTGCTGGCATCGTCCCCACCCCCAGCCTGGGGGTCT GGGCTGGGGCAGGGATTGCTCAGTGGAAGCAGGACTGGGGGTCTGGCTTGCCCCCTCCCTGGGCCTCCA TCACCCCTGAGCATCCCTCTGGACTCAGAGGGAACAAGGTGGGAGAGAGAGTTTGAGACAGCTCCGTGT GGAGAGCTTAGCCCCTGGAGGCAGCACAAGGAGGATGTGATATGTGGGGGAGTGAGCACTGGGTTGGGA GCCGGGTCCTGGTTTCCAATTTGGGTTCTGCTGTGTGACTCTGGGCAAGTCACTCTCCCTCTCTGGGCA TGTCTGCTACAAATGGACAAGATTATTTCAGAGGTCACTGAAGACTGTGATTACATGCACCTGCCTTAG AAGGTAGGATTTTCTTCCCAGGGACCTCCTATCACCCTACCCTGCTTCTTGAGGTCCCTGGAGCCCCAG GTGGGCTGAGGGGCAGGGAGCCGGCTGTGCCCAGTATGCCTCCTGGACCCTCCAGTTCTGCCACAGGTC TGCCGATGCCCTGTCCACTGCCTACACATGACAGACAAGTAACCCCCTCATGGGGGATGGGGACCTACC TGGCTCCTCAGCCAGCACCCAGCTTAACCCCTGCCATCCCATGCTGGGCCCTCCAGGCCAAGAGTCTCA GCTGGCCGAGAGTCCAGGCCTTGCCTCCCCCGACCGCCATGGAGGGGGCAGCCCGGCACAGCTGCTGGG AGCCCTTGTGTGTCTGGTCACACTTTTTAGGCGTCACGCCAAAGGCCAGCCTCCTGGCCCCAATACCCA TTTTGGAAGCCCCTGTGGCCGTGTGGATGTCGGTAACAGTTGTATAAAATAAATTCTATTTATCGCTAT TGTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001145657.3
Synonyms	RAP1GA1; RAP1GAP1; RAP1GAPII; RAPGAP
Summary	This gene encodes a type of GTPase-activating-protein (GAP) that down-regulates the activity of the ras-related RAP1 protein. RAP1 acts as a molecular switch by cycling between an inactive GDP-bound form and an active GTP-bound form. The product of this gene, RAP1GAP, promotes the hydrolysis of bound GTP and hence returns RAP1 to the inactive state whereas other proteins, guanine nucleotide exchange factors (GEFs), act as RAP1 activators by facilitating the conversion of RAP1 from the GDP- to the GTP-bound form. In general, ras subfamily proteins, such as RAP1, play key roles in receptor-linked signaling pathways that control cell growth and differentiation. RAP1 plays a role in diverse processes such as cell proliferation, adhesion, differentiation, and embryogenesis. Alternative splicing results in multiple transcript variants encoding distinct proteins. [provided by RefSeq, Aug 2011]
Locus ID	5909
MW	39.7

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