DMP1 (NM_001079911) Human 3' UTR Clone

Specifications

Product Data
Product Name	DMP1 (NM_001079911) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ARHP; ARHR; DMP-1
ACCN	NM_001079911
Insert Size	1067 bp
Sequence Data	Insert Sequence (showhide) >SC212052 3’UTR clone of NM_001079911 The sequence shown below is from the reference sequence of NM_001079911. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GATGACAATGACTGCCAAGACGGCTATTAGCATCAGCTGTCCTAAGAAGCAGTTGTCACATAAAGGAGT CTTAGGGACTTGAAAATGTATCATGATAACTATAATTTATTGATGTTTTGATCAAAAGAATAACCAGAT GCCATATTTTTCCTGAAAGGAATTGCTGGACATTACACTTGTTTTTAGGGTGTCATCATTTCACAGAGG TTTAAATACTGTGGAGTGACACCAGAACACAGCCAAAGAGGCTAGAAGCAAGAAAGGATCTGCATGATA ACTTTGCAGCTGAGATAGTTCCTAATTCATCAACGTAACAAACAAAGCTATTGGGTGTCCATGATATAC CAGGCACTATGCTAGGTGTTGAGAATGTAAAGCAGGTTAAGACTTGTTTCTTGCTCCTGAGGAGCGTAT AGAAGGACCCACAAAGCTACAGAGTTAAAGAGGGATATGTATAAGAGAAACAAGAATTGTTACAACCCA GTATGGTGAGTGCCAAGACAGAGAGCTATGAACACGATATCTATCTGGGAACACTGAGAAGGGTGACCA ATGCGTTGGAGAACGAGGGAGGGCTTCATAGCAGAAGACATTGGAGTTGGAAGGTTGCATAGGGTTTCC TCATTGGAGACCGGGAAATTCTATTCTTGGGATAAATAATAGTAAATTCTATAGGATTCAATACTTAGT TTGCAAAAGCACTTTGAAATTATGGCACAGTGAGTTGTTTTGGATAAGAAAATCTTTTTCTCCCAATTA ATTTACCAATTCATCATTTTTTTTTTTTTGTAGAACTCCCATAAACATCACCTTACTAATCACTGGTGA TGATAAGAAGGATTGGGTCAGGAAGAGTGGGAGAAAGAAATTCCTCTTTACGTAGATACTTTTTAGCTT TATTTTTTCTAAAATCAGTTTGCGTGCAATGCTAGAAAAAAACTGTTCTCTGAGTCCTTTACAGAGCAA AATTCTGTATGTAAGATTCAATTGATTTTTGACAAATACCATTTGAAATATTACCTCAACATAAAATAC TTGTTTTGTAATAAAGATTATAATACCCAGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001079911.3
Synonyms	ARHP; ARHR; DMP-1
Summary	Dentin matrix acidic phosphoprotein is an extracellular matrix protein and a member of the small integrin binding ligand N-linked glycoprotein family. This protein, which is critical for proper mineralization of bone and dentin, is present in diverse cells of bone and tooth tissues. The protein contains a large number of acidic domains, multiple phosphorylation sites, a functional arg-gly-asp cell attachment sequence, and a DNA binding domain. In undifferentiated osteoblasts it is primarily a nuclear protein that regulates the expression of osteoblast-specific genes. During osteoblast maturation the protein becomes phosphorylated and is exported to the extracellular matrix, where it orchestrates mineralized matrix formation. Mutations in the gene are known to cause autosomal recessive hypophosphatemia, a disease that manifests as rickets and osteomalacia. The gene structure is conserved in mammals. Two transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Jul 2008]
Locus ID	1758
MW	42.6

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