MBD1 (NM_002384) Human 3' UTR Clone

Specifications

Product Data
Product Name	MBD1 (NM_002384) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CXXC3; PCM1; RFT
ACCN	NM_002384
Insert Size	1035 bp
Sequence Data	Insert Sequence (showhide) >SC211938 3’UTR clone of NM_002384 The sequence shown below is from the reference sequence of NM_002384. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTTAAAAAACCTGGAGCTAGAAAGCAGTAGACTGGAGGCTTCTACAGACTGTAGGATTCAAGTCTGCAG GGCAGGCACTCGGGAAGGGAAGATGGATGTAAAGTGTGGGAGACCGAGGACACAGTGGAGCCCACGAGC ACGAGCTGGAACCCACGAGGATGGCCTGGAACCCATGTCAGTCTCTCACCACCTCCAGCTTCGATGATG TGGGTGTCCTGCAGAAGAAGCTGGTGCCCTTCCTCACAGAGTTAAATATGCATCTGGCCCAGGAATTAG AGAAGCTGAAAGGATGATCCTGGGGAAGGTGGAGCAGCTGCAGGCCTGGCTGCAGGCCTGACTACTGCC CACACCAACGAGGTGATCTAGCAGATACATGGCAACGTGTGAACTGCAACAACGCCTGGTGCCCCAGCA CCAACCTTCCAAGTGTAAAAACAATGTGCTGCTGCTTCACTTCCGCCCTCCGGTTATCAAGCAAAATGT CTCTTGTGGCCCATCTTACTGGAAGAGAGTTCCGGGAAACATAGCCTCACCAAGGTGACACATTACAAA GCCACCCTACCATGAATCCGCTCCCAAGGGTCTCACTGCTCACCTGAGGATAACTCAATATAACTATGT GGCTGAAAATGCAAAGCTGAAGACCATGGATTTCATGGTGATTCCAGCAAGTACAGAGATTCTATGAAG CCCACCCAGAAAAAACTTGCTGGTCCTGGCTATTTTTGTGTCATTTATTCAAGTATTGAGAACCTGGCC TGTGGTAGGCACTGTACTTAATACTAGGATACAGAAATGCAAAAGATACGGCCCATGCAATTTTATTAA ATGCATCAATATGTATTACAAATGGTGAATGGATTTCCAACTTTATCATGGAATTTAATGCTGAATATA TAGAATTCAGAAAATTGTTGGGAGGACAGCCCTTTTGTGAACCTTGTTTGGGGCACAGTAGGAATTGGA AATAATTTAGTTTCTATCTCTAAGCTGTTCTATTTTAAAATTATTTTTAAATTTTTATTGTCCCACTTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002384.3
Synonyms	CXXC3; PCM1; RFT
Summary	The protein encoded by this gene is a member of a family of nuclear proteins related by the presence of a methyl-CpG binding domain (MBD). These proteins are capable of binding specifically to methylated DNA, and some members can also repress transcription from methylated gene promoters. This protein contains multiple domains: MBD at the N-terminus that functions both in binding to methylated DNA and in protein interactions; several CXXC-type zinc finger domains that mediate binding to non-methylated CpG dinucleotides; transcriptional repression domain (TRD) at the C-terminus that is involved in transcription repression and in protein interactions. Numerous alternatively spliced transcript variants encoding different isoforms have been noted for this gene.[provided by RefSeq, Feb 2011]
Locus ID	4152
MW	38.3

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