HTRA3 (NM_053044) Human 3' UTR Clone

Specifications

Product Data
Product Name	HTRA3 (NM_053044) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	Prsp; Tasp
ACCN	NM_053044
Insert Size	992 bp
Sequence Data	Insert Sequence (showhide) >SC211844 3’UTR clone of NM_053044 The sequence shown below is from the reference sequence of NM_053044. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TTCAGCATCGCACCTGAGGTGGTCATGTGAGGGGCGCATTCCTCCAGCGCCAAGCGTCAGAGCCTGCAG ACAACGGAGGGCAGCGCCCCCCCGAGATCAGGACGAAGGACCACCGTCGGTCCTCAGCAGGGCGGCAGC CTCCTCCTGGCTGTCCGGGGCAGAGCGGAGGCTGGGCTTGGCCAGGGGCCCGAATTTCCGCCTGGGGAG TGTTGGATCCACATCCCGGTGCCGGGGAGGGAAGCCCAACATCCCCTTGTACAGATGATCCTGAAAGTC ACTTCCAAGTTCTCCGGATATTCACAAAACTGCCTTCCATGGAGGTCCCCTCCTCTCCTAGCTTCCCGC CTCTGCCCCTGTGAACACCCATCTGCAGTATCCCCTGCTCCTGCCCCTCCTACTGCAGGTCTGGGCTGC CAAGCTTCTTCCCCCCTGACAAACGCCCACCTGACCTGAGGCCCCAGCTTCCCTCTGCCCTAGGACTTA CCAAGCTGTAGGGCCAGGGCTGCTGCCTGCCAGCCTGGGGTCCCTGGAGGACAGGTCACATCTGATCCC TTTGGGGTGCGGGGGTGGGGTCCAGCCCAGAGCAGGCACTGAGTGAATGCCCCCTGGCTGCGGAGCTGA GCCCCGCCCTGCCATGAGGTTTTCCTCCCCAGGCAGGCAGGAGGCCGCGGGGAGCACGTGGAAAGTTGG CTGCTGCCTGGGGAAGCTTCTCCTCCCCAAGGCGGCCATGGGGCAGCCTGCAGAGGACAGTGGACGTGG AGCTGCGGGGTGTGAGGACTGAGCCGGCTTCCCCTTCCCACGCAGCTCTGGGATGCAGCAGCCGCTCGC ATGGAAGTGCCGCCCAGAGGCATGCAGGCTGCTGGGCACCACCCCCTCATCCAGGGAACGAGTGTGTCT CAAGGGGCATTTGTGAGCTTTGCTGTAAATGGATTCCCAGTGTTGCTTGTACTGTATGTTTCTCTACTG TATGGAAAATAAAGTTTACAAGCACA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_053044.5
Synonyms	Prsp; Tasp
Summary	Serine protease that cleaves beta-casein/CSN2 as well as several extracellular matrix (ECM) proteoglycans such as decorin/DCN, biglycan/BGN and fibronectin/FN1. Inhibits signaling mediated by TGF-beta family proteins possibly indirectly by degradation of these ECM proteoglycans (By similarity). May act as a tumor suppressor. Negatively regulates, in vitro, trophoblast invasion during placental development and may be involved in the development of the placenta in vivo. May also have a role in ovarian development, granulosa cell differentiation and luteinization (PubMed:21321049, PubMed:22229724).[UniProtKB/Swiss-Prot Function]
Locus ID	94031
MW	34.6

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