PERK (EIF2AK3) (NM_004836) Human 3' UTR Clone

Specifications

Product Data
Product Name	PERK (EIF2AK3) (NM_004836) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	PEK; PERK; WRS
ACCN	NM_004836
Insert Size	1025 bp
Sequence Data	Insert Sequence (showhide) >SC211792 3’UTR clone of NM_004836 The sequence shown below is from the reference sequence of NM_004836. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AACTCCCATAGCCCTTTGCCAAGCAATTAGCCTTAAGTTGTGCTAGCAACCCTAATAGGTGATGCAGAT AATAGCCTACTTCTTAGAATATGCCTGTCCAAAATTGCAGACTTGAAAAGTTTGTTCTTCGCTCAATTT TTTTGTGGACTACTTTTTTTATATCAAATTTAAGCTGGATTTGGGGGCATAACCTAATTTGAGCCAACT CCTGAGTTTTGCTATACTTAAGGAAAGGGCTATCTTTGTTCTTTGTTAGTCTCTTGAAACTGGCTGCTG GCCAAGCTTTATAGCCCTCACCATTTGCCTAAGGAGGTAGCAGCAATCCCTAATATATATATATAGTGA GAACTAAAATGGATATATTTTTATAATGCAGAAGAAGGAAAGTCCCCCTGTGTGGTAACTGTATTGTTC TAGAAATATGCTTTCTAGAGATATGATGATTTTGAAACTGATTTCTAGAAAAAGCTGACTCCATTTTTG TCCCTGGCGGGTAAATTAGGAATCTGCACTATTTTGGAGGACAAGTAGCACAAACTGTATAACGGTTTA TGTCCGTAGTTTTATAGTCCTATTTGTAGCATTCAATAGCTTTATTCCTTAGATGGTTCTAGGGTGGGT TTACAGCTTTTTGTACTTTTACCTCCAATAAAGGGAAAATGAAGCTTTTTATGTAAATTGGTTGAAAGG TCTAGTTTTGGGAGGAAAAAAGCCGTAGTAAGAAATGGATCATATATATTACAACTAACTTCTTCAACT ATGGACTTTTTAAGCCTAATGAAATCTTAAGTGTCTTATATGTAATCCTGTAGGTTGGTACTTCCCCCA AACTGATTATAGGTAACAGTTTAATCATCTCACTTGCTAACATGTTTTTATTTTTCACTGTAAATATGT TTATGTTTTATTTATAAAAATTCTGAAATCAATCCATTTGGGTTGGTGGTGTACAGAACACACTTAAGT GTGTTAACTTGTGACTTCTTTCAAGTCTAAATGATTTAATAAAACTTTTTTTAAATTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004836.7
Synonyms	PEK; PERK; WRS
Summary	The protein encoded by this gene phosphorylates the alpha subunit of eukaryotic translation-initiation factor 2, leading to its inactivation, and thus to a rapid reduction of translational initiation and repression of global protein synthesis. This protein is thought to modulate mitochondrial function. It is a type I membrane protein located in the endoplasmic reticulum (ER), where it is induced by ER stress caused by malfolded proteins. Mutations in this gene are associated with Wolcott-Rallison syndrome. [provided by RefSeq, Sep 2015]
Locus ID	9451
MW	38.7

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