TIE2 (TEK) (NM_000459) Human 3' UTR Clone

Specifications

Product Data
Product Name	TIE2 (TEK) (NM_000459) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CD202B; GLC3E; TIE-2; TIE2; VMCM; VMCM1
ACCN	NM_000459
Insert Size	972 bp
Sequence Data	Insert Sequence (showhide) >SC211718 3’UTR clone of NM_000459 The sequence shown below is from the reference sequence of NM_000459. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATTGACTGTTCTGCTGAAGAAGCGGCCTAGGACAGAACATCTGTATACCCTCTGTTTCCCTTTCACTGG CATGGGAGACCCTTGACACCTGCTGAGAAAACATGCCTCTGCCAAAGGATGTGATATATAAGTGTACAT ATGTGCTGTACACCTGGGACCTTCACCACTGTAGATCCCATGCATGGATCTATGTAGTATGCTCTGACT CTAATAGGACTGTATATACTGTTTTAAGAATGGGCTGAAATCAGAATGCCTGTTTGTGGTTTCATATGC AATAATATATTTTTTTAAAAATGTGGACTTCATAGGAAGGCGTGAGTACAATTAGTATAATGCATAACT CATTGTTGTCCTAGATATTTTGATATTTACCTTTATGTTGAATGCTATTAAATGTTTTCCTGTGTCAAA GTAAAATATTGTTAATAAACCTAACAATGACCCTGATAGTACAGGTTAAGTGAGAGAACTATATGAATT CTAACAAGTCATAGGTTAATATTTAAGACACTGAAAAATCTAAGTGATATAAATCAGATTCTTCTCTCT CAATTTTATCCCTCACCTGTAGCAGCCAGTCCCGTTTCATTTAGTCATGTGACCACTCTGTCTTGTGTT TCCACAGCCTGCAAGTCAGTCCAGGATGCTAACATCTAAAAATAGACTTAAATCTCATTGCTTACAAGC CTAAGAATCTTTAGAGAAGTATACATAAGTTTAGGATAAAATAATGGGATTTTCTTTTCTTTTCTCTGG TAATATTGACTTGTATATTTTAAGAAATAACAGAAAGCCTGGGTGACATTTGGGAGACATGTGACATTT ATATATTGAATTAATATCCCTACATGTATTGCACATTGTAAAAAGTTTTAGTTTTGATGAGTTGTGAGT TTACCTTGTATACTGTAGGCACACTTTGCACTGATATATCATGAGTGAATAAATGTCTTGCCTACTCAC GTCTCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000459.5
Synonyms	CD202B; GLC3E; TIE-2; TIE2; VMCM; VMCM1
Summary	This gene encodes a receptor that belongs to the protein tyrosine kinase Tie2 family. The encoded protein possesses a unique extracellular region that contains two immunoglobulin-like domains, three epidermal growth factor (EGF)-like domains and three fibronectin type III repeats. The ligand angiopoietin-1 binds to this receptor and mediates a signaling pathway that functions in embryonic vascular development. Mutations in this gene are associated with inherited venous malformations of the skin and mucous membranes. Alternative splicing results in multiple transcript variants. Additional alternatively spliced transcript variants of this gene have been described, but their full-length nature is not known. [provided by RefSeq, Feb 2014]
Locus ID	7010
MW	37.4

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