CFHR5 (NM_030787) Human 3' UTR Clone

Specifications

Product Data
Product Name	CFHR5 (NM_030787) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CFHL5; CFHR5D; FHR-5; FHR5
ACCN	NM_030787
Insert Size	1025 bp
Sequence Data	Insert Sequence (showhide) >SC211621 3’UTR clone of NM_030787 The sequence shown below is from the reference sequence of NM_030787. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GGGAAATTTGAATATCCTATATGTGAATGAAGCAAGCATAATTTTCCTGAATATATTCTTCAAACATCC ATCTATGCTAAAAGTAGCCATTATGTAGCCAATTCTGTAGTTACTTCTTTTATTCTTTCAGGTGTTGTT TAACTCAGTTTTATTTAGAACTCTGGATTTTTAGAGCTTTAGAAATTTGTAAGCTGAGAGAACAATGTT TCACTTAATAGGAGGGTGTCTTAGTCCATATTACATTGTTATAACAGAGTATCACAGACTGGATAACTT CTAACCAATAGTTTATTTGTTTCATAAATCTAAAAGCTGAGAAGTCCAAGATGGTGGGGCTGCCTCTGG TGAGGGTCTTCTCGAAGCATCATAATATGCTGGAAGGCATCACAACATGGTGGAAGGGATCACGTGGCA AAAGAGCATGTACATGGGAGTGAGAGAAAAAGAGAGAGAGAGACAGAGTGGCGGGGGCGGGGAGGAGCG CAAACTCATCCTTTATAAAGACACCACTCCTGAGATAACAATCCAATCCCATGATAATGACATTAATCC ATTCAAGAAGATAGAGCTCTCGTGACTTAATCACCTTCTAAAGATCTCACCTGACAACACTGTTGCATT GGCAGTTAAGTTTCCACGTAAACTTTCGGGGACACATTCAAACCACAGGAGAAACTCAAATTGTTCCTG GGCAAATCACAACATGGGGAATTTTATTCATAAATGTCCACAGAAACAGTAAATGTTCTCGCTTCAGTA CTTAATTCATCTAATCCCTCCTGTTTGTCTCAAATTATAGGATAACTTTGAAACTTTCTGAATTAACGT TATTTAAAAGGAAATGTAGATGTTATTTTAGTCTCTATCTTCATGTTATTATCACTTAAAAACCTGCGA AAGCTGTCAACTTTTGTGGTTGTAGCAAGTATTAATAAATATTTATAAATCCTCTAATGTAAGTCTAGC TACCTATCCAATACTAAATACCCCTTAAAGTATTAAATGCACTATCTGCTGTAAAAGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_030787.4
Synonyms	CFHL5; CFHR5D; FHR-5; FHR5
Summary	This gene is a member of a small complement factor H (CFH) gene cluster on chromosome 1. Each member of this gene family contains multiple short consensus repeats (SCRs) typical of regulators of complement activation. The protein encoded by this gene has nine SCRs with the first two repeats having heparin binding properties, a region within repeats 5-7 having heparin binding and C reactive protein binding properties, and the C-terminal repeats being similar to a complement component 3 b (C3b) binding domain. This protein co-localizes with C3, binds C3b in a dose-dependent manner, and is recruited to tissues damaged by C-reactive protein. Allelic variations in this gene have been associated, but not causally linked, with two different forms of kidney disease: membranoproliferative glomerulonephritis type II (MPGNII) and hemolytic uraemic syndrome (HUS). [provided by RefSeq, Jan 2010]
Locus ID	81494
MW	38.8

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