ICAD (DFFA) (NM_004401) Human 3' UTR Clone
CAT#: SC211368
3' UTR clone of DNA fragmentation factor 45kDa alpha polypeptide (DFFA) transcript variant 1 for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
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经常一起买 (2)
Specifications
Product Data | |
Product Name | ICAD (DFFA) (NM_004401) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | DFF-45; DFF1; ICAD |
ACCN | NM_004401 |
Insert Size | 2000 bp |
Sequence Data |
>SC211368 3’UTR clone of NM_004401
The sequence shown below is from the reference sequence of NM_004401. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCTAAGCGAGCCAGACAGGATCCCACATAGCAGCAGCGGGAAGTGTGCCAAGGAAGCTCTGTGGCGTTG TGTTATTGGTAGACACCCTCAGCCTCATCATTTGACTACCTATGTACTACTCTACCCCCTGCCTTAGAG CACCTTCCAGAGAAGCTATTCCAGGTCTCAACATACGCCGTTCCACCAATTTTTTTTTTAGCCCCACCA GCTTCAGGACTTCTGCCAATTTTGAATGATATAGCTGCACCAACAATATCCCGCCTCCTCTAATTACAT ATGATGTTCTCTGTTCAAAAGTAATTGGCAGTGATTGGCCAGGCGCAGTGGCTCACGCCTGTAATCCCA GCACTGGGAGGCCGAGGGGGGCGGATCGTGAAGTCAGGAGATCGAGACCATCCTGGCTAACATGGTGAA ACCCTGTCTCTACTAAAAATACAAAAAAAATTAGCCAGCCATGGTGGCGGGCGCCTGTAATCCCAGCTA CTTGGGAGGCTGAGGCAGGAGAATGGCATGAACCTGGGAGGCAGAGCTTGCAGTGAGCTGAGATTGCGC CACTGCACTCCAGCCTGGGCAACAGAGCGAGACTCCGTCTCAAAAAAAAAAAAAAAAAAAGTAATTGGC AGTGACTATGGGCGCACTGCCTAACATTTAGCCCTGCCCCATATGGAACATGTTAAAAAAAAAAAAAGC CAGGCCGAGCGTGTTGGCTCACGCTTGTAATCCCAGCACTTTGGGAGGCCGAGGCGGGTGGATCACGAG GTCAGGAGATCGAGACCATCCTGGCTAACACAGTGAAACGTGTTTTTACTAAAAGTACAAAAAACTAGC TGGGCGTGGTGGCAGGAGCCTGTAGTCCCAGCTACTCGGGAGGCTGAGGCAGGAGAATTGCTTGAACCG GGGAGGCAGAAGTTGCAGTGAGCCGAGATTATGCCACTGTACTCCAGCCTGGGTGACAGAGTGACACTC TGTCTCAAAAAAAAAAAAAAAAAGGACAGGCACGACAGTGGCTCACACCTTTGATCCCAGCACTTTGGA GGCCGATGCAGGCGGATCACATGAGGTCAGGAGTTCAAGACCAACCTGGCCAATATGGTGAAACCCCGT CTCTACTAAAAATACAAAAATTAGCTGGGCATGATGGCGGGTGCCTGTAATCCCAGCTACTCGGTAGGC AGAGGTTGCAGTGAGCTGAGAGCGCACCACTGCACTCCAGCCTGGGTGACAGAGCTAGACTCCGTATCT CAAGAAAAAAAAAAAGTTTTGTTTTGTTTTTTTGAGACAGAGTCTCACTCTGTCACCTAGTCTGGAGTG CAGTGGCACATTCTCGGCTCACTGCAACCCCCACCTCCCAGGTTCAAGCGATTCTCCTGTTTCAGCCTC CTGAGCAGCTGGGATTACAGGCACGTGCCACCATGCCCGGCTAATTTTTGTATTTTTAGTAGAGACAGG GTTTTGTCACATTGGCCAGGCTGGTCTCAAACTCCTGACCTCAGGTGATCCACCCACCTCAGCCTCCCA AAGTGCTGGGATTACAGGTGTGAGCCACCACCCCTGGCCAGAAAAAAAAGCTTTTAAATAAAGTAATTG TCAGCTTAGGCAACATAGCAAGACCCTGTCTCTACAAAAAAAAAATTTAAGTTAGCCAGGCATGGTGGC ACTGACCTATAATCCTAGCTACTCTGGAGGCTAAGGCGAGAGTATCACTTGAGCCCAGGAGCTCAAGGC TGATCATGCCACCATACTCCAGCCTGGATGATAGAGTAAGACCCTACTTTTTTTTTTTTTTTTTTAAAA AGGTAACCATCAAGGGCAATGAAAAGAAATGGTCGTATTTCCAATTCATTATCCTTATTCTGAAGATAG TACGGCAGAATTTTAAGCAGAGATAGTGGTGAAGATGGTGACATTATAGAGTGTTGACTATGGCCACAA TCTTGTTTCTCCAGTTAATGAATTTTTTTATGTGTTTGTTTAAAGATACATATTAAGCTTGTAGACCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_004401.3 |
Synonyms | DFF-45; DFF1; ICAD |
Summary | Apoptosis is a cell death process that removes toxic and/or useless cells during mammalian development. The apoptotic process is accompanied by shrinkage and fragmentation of the cells and nuclei and degradation of the chromosomal DNA into nucleosomal units. DNA fragmentation factor (DFF) is a heterodimeric protein of 40-kD (DFFB) and 45-kD (DFFA) subunits. DFFA is the substrate for caspase-3 and triggers DNA fragmentation during apoptosis. DFF becomes activated when DFFA is cleaved by caspase-3. The cleaved fragments of DFFA dissociate from DFFB, the active component of DFF. DFFB has been found to trigger both DNA fragmentation and chromatin condensation during apoptosis. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008] |
Locus ID | 1676 |
MW | 75.6 |
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