uPA (PLAU) (NM_002658) Human 3' UTR Clone

Specifications

Product Data
Product Name	uPA (PLAU) (NM_002658) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ATF; BDPLT5; QPD; u-PA; UPA; URK
ACCN	NM_002658
Insert Size	959 bp
Sequence Data	Insert Sequence (showhide) >SC211329 3’UTR clone of NM_002658 The sequence shown below is from the reference sequence of NM_002658. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACCAAGGAAGAGAATGGCCTGGCCCTCTGAGGGTCCCCAGGGAGGAAACGGGCACCACCCGCTTTCTTG CTGGTTGTCATTTTTGCAGTAGAGTCATCTCCATCAGCTGTAAGAAGAGACTGGGAAGATAGGCTCTGC ACAGATGGATTTGCCTGTGCCACCCACCAGGGCGAACGACAATAGCTTTACCCTCAGGCATAGGCCTGG GTGCTGGCTGCCCAGACCCCTCTGGCCAGGATGGAGGGGTGGTCCTGACTCAACATGTTACTGACCAGC AACTTGTCTTTTTCTGGACTGAAGCCTGCAGGAGTTAAAAAGGGCAGGGCATCTCCTGTGCATGGGTGA AGGGAGAGCCAGCTCCCCCGACGGTGGGCATTTGTGAGGCCCATGGTTGAGAAATGAATAATTTCCCAA TTAGGAAGTGTAACAGCTGAGGTCTCTTGAGGGAGCTTAGCCAATGTGGGAGCAGCGGTTTGGGGAGCA GAGACACTAACGACTTCAGGGCAGGGCTCTGATATTCCATGAATGTATCAGGAAATATATATGTGTGTG TATGTTTGCACACTTGTGTGTGGGCTGTGAGTGTAAGTGTGAGTAAGAGCTGGTGTCTGATTGTTAAGT CTAAATATTTCCTTAAACTGTGTGGACTGTGATGCCACACAGAGTGGTCTTTCTGGAGAGGTTATAGGT CACTCCTGGGGCCTCTTGGGTCCCCCACGTGACAGTGCCTGGGAATGTATTATTCTGCAGCATGACCTG TGACCAGCACTGTCTCAGTTTCACTTTCACATAGATGTCCCTTTCTTGGCCAGTTATCCCTTCCTTTTA GCCTAGTTCATCCAATCCTCACTGGGTGGGGTGAGGACCACTCCTGTACACTGAATATTTATATTTCAC TATTTTTATTTATATTTTTGTAATTTTAAATAAAAGTGATCAATAAAATGTGATTTTTCTGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002658.6
Synonyms	ATF; BDPLT5; QPD; u-PA; UPA; URK
Summary	This gene encodes a secreted serine protease that converts plasminogen to plasmin. The encoded preproprotein is proteolytically processed to generate A and B polypeptide chains. These chains associate via a single disulfide bond to form the catalytically inactive high molecular weight urokinase-type plasminogen activator (HMW-uPA). HMW-uPA can be further processed into the catalytically active low molecular weight urokinase-type plasminogen activator (LMW-uPA). This low molecular weight form does not bind to the urokinase-type plasminogen activator receptor. Mutations in this gene may be associated with Quebec platelet disorder and late-onset Alzheimer's disease. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Jan 2016]
Locus ID	5328
MW	35

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