DROSHA (NM_013235) Human 3' UTR Clone

Specifications

Product Data
Product Name	DROSHA (NM_013235) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ETOHI2; HSA242976; RANSE3L; RN3; RNASE3L; RNASEN
ACCN	NM_013235
Insert Size	968 bp
Sequence Data	Insert Sequence (showhide) >SC211256 3’UTR clone of NM_013235 The sequence shown below is from the reference sequence of NM_013235. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCAGATGAGACTGAAGACATCAAGAAATAAAGGAGGGCATGCAAGTGTGGAGTATTTACTTGCTCAGTA ACTGTGACTGTTGTCTATTGAGACCTAGCCTAGTTTTCCTGCAGACAATGAATGAAGTGTGCTCATTGA AATAAAATACAGAGTCAAATCGCTATTGTTGTTTTAATGATCTGTTTTTAGCTGGATGGTCTTTATTAC AAAGTATTAGATTTTTCTTCTATTTAACGGAAAACTTGACTTTGGTGAATGTGCATTACTTCCTTTTAT TTTGCTCTTTAAATAATAAAATTCAAGAAGCATATTCTATGTGGAATAGATCCTGTTTTTCCATCTGTG TCCCAGATTGTGACCCTAGACTTTCAATTGACAAGTAAAAAATTGACTTTACTAGACATTTTGACTGTG CTCTAGTAACATCTATCCTTTTTCAAATCTCTGGATTTTTAAGTAGATTGTTCAGCTTTCATCCGGTGG CTGTTCATCAAGTTATCAGCTGCAAATATTGAACTTACCTCTCTCTAAGCAGTGAGTGTTTTGTAGAAG GAATCCGTTTAACAATTAATTGGCTAATGGGAGAAGGGGAAAGACTGATATTCAAGTCATACAGATTCT TTGAATCATTAGAATAGGAGAGAAATCATGATTCTAAGCCAGGCCACACTTTAAACCAAGTGCTCTCAC CCTGGGGTTAGTGGAACCTTTAAGAAGTTAATGAACAGACTTCAAGGAAGTCAAAAACCTCCCAATACT ATATTCAATTTTCTGTGTGTGTTTGAGATTTGAGAGGGCATGGGGAGCAGGAAGGAGGAGGGTTTATAG CTTTTATCAGCCTCTCTAAGTGGGCCCTGCAGTAAAAGGCTAACATGACATTCAAAGACATAACATTTT AAAAAAAGTTATTCCAAACTAAACATCACTGGTTTCTTATTAATAAAGGCAAAACTTCTTTGTAAAACA AA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_013235.5
Synonyms	ETOHI2; HSA242976; RANSE3L; RN3; RNASE3L; RNASEN
Summary	This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer. [provided by RefSeq, Sep 2016]
Locus ID	29102
MW	36.5

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