DROSHA (NM_001100412) Human 3' UTR Clone

CAT#: SC211255

3' UTR clone of ribonuclease type III nuclear (RNASEN) transcript variant 2 for miRNA target validation



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CNY 4,845.00


货期*
3周

规格
    • 10 ug

Product images

经常一起买 (2)
Firefly luciferase assay kit, 150 assays
    • 1 kit

CNY 1,520.00


DH5α Chemically Competent Cells (≥10^8 cfu/μg of pUC19 DNA)
    • 5 x 200 ul

CNY 1,280.00

Specifications

Product Data
Product Name DROSHA (NM_001100412) Human 3' UTR Clone
Vector pMirTarget
Synonyms ETOHI2; HSA242976; RANSE3L; RN3; RNASE3L; RNASEN
ACCN NM_001100412
Insert Size 968 bp
Sequence Data
>SC211255 3’UTR clone of NM_001100412
The sequence shown below is from the reference sequence of NM_001100412. The complete sequence of this clone may contain minor differences, such as SNPs.
Blue=Stop Codon Red=Cloning site

GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG
TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC
CCAGATGAGACTGAAGACATCAAGAAATAAAGGAGGGCATGCAAGTGTGGAGTATTTACTTGCTCAGTA
ACTGTGACTGTTGTCTATTGAGACCTAGCCTAGTTTTCCTGCAGACAATGAATGAAGTGTGCTCATTGA
AATAAAATACAGAGTCAAATCGCTATTGTTGTTTTAATGATCTGTTTTTAGCTGGATGGTCTTTATTAC
AAAGTATTAGATTTTTCTTCTATTTAACGGAAAACTTGACTTTGGTGAATGTGCATTACTTCCTTTTAT
TTTGCTCTTTAAATAATAAAATTCAAGAAGCATATTCTATGTGGAATAGATCCTGTTTTTCCATCTGTG
TCCCAGATTGTGACCCTAGACTTTCAATTGACAAGTAAAAAATTGACTTTACTAGACATTTTGACTGTG
CTCTAGTAACATCTATCCTTTTTCAAATCTCTGGATTTTTAAGTAGATTGTTCAGCTTTCATCCGGTGG
CTGTTCATCAAGTTATCAGCTGCAAATATTGAACTTACCTCTCTCTAAGCAGTGAGTGTTTTGTAGAAG
GAATCCGTTTAACAATTAATTGGCTAATGGGAGAAGGGGAAAGACTGATATTCAAGTCATACAGATTCT
TTGAATCATTAGAATAGGAGAGAAATCATGATTCTAAGCCAGGCCACACTTTAAACCAAGTGCTCTCAC
CCTGGGGTTAGTGGAACCTTTAAGAAGTTAATGAACAGACTTCAAGGAAGTCAAAAACCTCCCAATACT
ATATTCAATTTTCTGTGTGTGTTTGAGATTTGAGAGGGCATGGGGAGCAGGAAGGAGGAGGGTTTATAG
CTTTTATCAGCCTCTCTAAGTGGGCCCTGCAGTAAAAGGCTAACATGACATTCAAAGACATAACATTTT
AAAAAAAGTTATTCCAAACTAAACATCACTGGTTTCTTATTAATAAAGGCAAAACTTCTTTGTAAAACA
AA
ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA
CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites SgfI-MluI     
OTI Disclaimer Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq NM_001100412.2
Synonyms ETOHI2; HSA242976; RANSE3L; RN3; RNASE3L; RNASEN
Summary This gene encodes a ribonuclease (RNase) III double-stranded RNA-specific ribonuclease and subunit of the microprocessor protein complex, which catalyzes the initial processing step of microRNA (miRNA) synthesis. The encoded protein cleaves the stem loop structure from the primary microRNA (pri-miRNA) in the nucleus, yielding the precursor miRNA (pre-miRNA), which is then exported to the cytoplasm for further processing. In a human cell line lacking a functional copy of this gene, canonical miRNA synthesis is reduced. Somatic mutations in this gene have been observed in human patients with kidney cancer. [provided by RefSeq, Sep 2016]
Locus ID 29102
MW 36.5
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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