Twinkle (TWNK) (NM_021830) Human 3' UTR Clone

Specifications

Product Data
Product Name	Twinkle (TWNK) (NM_021830) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ATXN8; C10orf2; IOSCA; MTDPS7; PEO; PEO1; PEOA3; PRLTS5; SANDO; SCA8; TWINL
ACCN	NM_021830
Insert Size	923 bp
Sequence Data	Insert Sequence (showhide) >SC211019 3’UTR clone of NM_021830 The sequence shown below is from the reference sequence of NM_021830. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CAGCCAGACACCTCCAAGCGTTCAAAGTGAAGGCCGTGCAGAGCTGGTCACTGAAATGAGCCTGATAGG ATAGGCTGGAGCATAAAACTCTGCAAGGGCTCCTCTATCCTGTGGTCCTGAGCTGTGTGCCCTTCTCAG TCTGAGGGGCCTAACCTAGAGCAGGTTTCCATAGTGAGAAAATTCAATGTAGCAGACTACTGAGAAACT ACTGTGTTGCTCAGGCTTTGTTTGAGGTCCTGTATATACAGCACTGAAAAGAGAGATAAAGTCCCTGCC TGCATGCATTCTGGCGGAAGAGACAAGCAAGCAATGAACAAATTAGCAGAAAACCTAGTTTTAGTGAAA AATGCTGTAAAGAAAATAGAAATGCGATAGAGTGCTGGCAGGCTAGTGTAGATAAGTGGTCTGAAAAGG TGTCTCTGAGCCGAGGGCATGTGAGCTGGGGCCTAAACAACTAGAAGGAGAGAGCCACGTGAACATCCG GCGAAGGGGACCCAGGCAGAGAGAAAAGGAAATCCAAGCCCTGAGGTAGGAATGAGCAGGTCAGATTCA AGGCAGTGAGGTCAGGCCGCATGAACCTGGAGGGGAATCGGGGACTTCATGCGAAACTCCAGCCTAGGC TTTCAAAGTCAAAGGGTGATACAGTGGGTACCAAGCTCCTCTGCTCCCCACTTTGTAGAGCCTAGCATG AGGTGGCATGTACTAGAATTGGATCCTAGGTGCTTAGCCCTGCAATATCAGGGCCTCACTGGTGGGAGC TGCCTCGGGCTGGGTTGCTTGGTCATAGAGCCATAGAAGGAAGCTGTCAGCCCGGAGTGCCTGCCACCT AGACACTGATGCCATTGTGTGCTGCCTCAAGACTGCTGGAGTCAGGACATTTTATAGAGCCTTTTCCAG TTTTACTAAAAAATTTTTCCATTGCC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_021830.5
Synonyms	ATXN8; C10orf2; IOSCA; MTDPS7; PEO; PEO1; PEOA3; PRLTS5; SANDO; SCA8; TWINL
Summary	This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Aug 2009]
Locus ID	56652
MW	34.3

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.