Supervillin (SVIL) (NM_003174) Human 3' UTR Clone

Specifications

Product Data
Product Name	Supervillin (SVIL) (NM_003174) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	MFM10
ACCN	NM_003174
Insert Size	938 bp
Sequence Data	Insert Sequence (showhide) >SC211009 3’UTR clone of NM_003174 The sequence shown below is from the reference sequence of NM_003174. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AACCTGAAGAAAGCAAAAGGCCTGTTCTGAGTGGGGAGACGCCAGAGGAGCCTCACGGTCACGTCCAAC AACACCACTGCACCAGGGAAATGGATATATATTTTTGGACTGGTGTTTTTCACAAAGTATTTTTCAATC AGAGTTTTCAGAACCTGACATTGTTAAAGATACTGCTTGTCCCGGAGTTGTGTATTTTGTAAATGTTCA AGGGAACTGTTTGGAAACTTCTTTCCACCATTCAGGAGGTTATCAGAATTAATAAAAGTATCTGTTATG TGCACTTAAGCCGCAGCTGCTATAGATAGCACTGCCTTCTTGTTCCAGCTAGGCAATGCCTTTTTTTTT TTTTTTTGAAGCAGTTCTCTTTATAAAGTGTTATTTTGATAGTTTGTGGATTCTAAAATATATATATAT TTATATAAACACCATATAAGTCAAATATGTATTTAACAAAGCAATATGTATTCATTCACTTTCAAGATT TGTTTTGGTGTCAAAATAACATGAAAAGGTAGATGGAGTTGCTTCTGTTGAATTAGCTCTGCCACCAAT ATGTATCTTCATACACGTTTGGAAATGTTTCCTGCAGCATTAGGTATGACTTGTTCTGAGTACTGCTTC CGGTGCTAAAATGAACAAAGAATTTGTACTTAATGGCATGGACTCTGGAGAATCTATGCGAATCAACCT TTCTACCTTAATATCTCCCCAAAAATGTATAGTGCCTTGTTTTTATGTACAGTTTATATACAGAAAAGT TTGCTCTGCATTTTTGATGATGGTTTGGAACATTATCTACAATTTTACTCTCAAATAGTCAAAATAAAA ACATCTCAATTTCTAATACCGGTTGTAAACAGTACACATGTCATTTTGTGATATAGGACTCCCAAATAA AAGTATCAGAATAAACACAACAATTAACTGGTAAAAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003174.3
Synonyms	MFM10
Summary	This gene encodes a bipartite protein with distinct amino- and carboxy-terminal domains. The amino-terminus contains nuclear localization signals and the carboxy-terminus contains numerous consecutive sequences with extensive similarity to proteins in the gelsolin family of actin-binding proteins, which cap, nucleate, and/or sever actin filaments. The gene product is tightly associated with both actin filaments and plasma membranes, suggesting a role as a high-affinity link between the actin cytoskeleton and the membrane. The encoded protein appears to aid in both myosin II assembly during cell spreading and disassembly of focal adhesions. Several transcript variants encoding different isoforms of supervillin have been described. [provided by RefSeq, Apr 2016]
Locus ID	6840
MW	36.7

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