Manic Fringe (MFNG) (NM_002405) Human 3' UTR Clone

Specifications

Product Data
Product Name	Manic Fringe (MFNG) (NM_002405) Human 3' UTR Clone
Vector	pMirTarget
ACCN	NM_002405
Insert Size	930 bp
Sequence Data	Insert Sequence (showhide) >SC210963 3’UTR clone of NM_002405 The sequence shown below is from the reference sequence of NM_002405. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCCTGGTGTCCCCAGCTGGGTGCCCGATGAATCCTGAACTGCTGGGCAAAGGTTGGGCAGAGACTTCTG GGTGTGCCTTGGCTCCCAAGGTGGCACTGTGGGTCCCTGGCAAGTGTCTTGTGATAGGCAGTCCCTGGC AGGGCCTTCGGGTGGTTGGCAAGCCCAGGATCTGAGTGGCAATTGGCACTGAAGGCACCCCAGGCCCCT GGGAGGTGAGTTAGACAGCCCAGGGGACCAGGTGGACCAGGTGGTGGCCAGAGAGGCTCCAGGGGCTAG ACTCCCTCAGGAGGCTGAATTGAAAAAGGGCAGGGGGCACTTGAGCTGGGCTGGGGCTCAGGGGTCCTA ACCCTTTAGGCAGTGACATGGCCTCTGGGTGGGGTCTGGCCGTTGGCCCTGGCTAATGTCTCTCAGTCA TTCCCCTGGGGCTCAAGCGCTGGGCCGCCCACTCCTGCCTCCCTCATCTGTGTCCCGAGTTCCTGAAGG GACATGGGTGGAATGATGGCAGAATCCAGGGTCTGCAGCACCTGCTGTTGTTGCCAACCAGTCTCCCAA AGCTCCTTGCTCCCCACCCCTTGCGAACAGGACCAGATTTTGTTTGGAGCCTCAGCATGCCGGGGCCCA GATGATGGAGCATAACGGGTCCCAGCCAATTGTGATGATCCTTTTTGCTCATTTCCCAGCCTTTCTTGC TGTTAGGGGCTACCATGGGACCAGCTCTGGCCAGAGGGAACTAAGCAAATCCAATAGAGATGTTTCTGG GGAAGGTTTTGCAGCCCACTCCCCATCTTCCTGCTATAAATGTGGGTGTGATGGCTGGATCTGGGGCAG CCACCTTGCTACCATGAAGGAAAGGCCAAGACAATCATCCACAGCTATTCCCTCCAGCATCTGGTTCTG TACAAAAATTAAATGCTTATTTGTTTAAGTCTC ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002405.4
Summary	This gene is a member of the glycosyltransferase 31 gene family. Members of this gene family, which also includes the LFNG (GeneID: 3955) and RFNG (GeneID: 5986) genes, encode evolutionarily conserved glycosyltransferases that act in the Notch signaling pathway to define boundaries during embryonic development. While their genomic structure is distinct from other glycosyltransferases, these proteins have a fucose-specific beta-1,3-N-acetylglucosaminyltransferase activity that leads to elongation of O-linked fucose residues on Notch, which alters Notch signaling. The protein encoded by this gene may control Notch signaling in claudin-low breast cancer. [provided by RefSeq, May 2018]
Locus ID	4242
MW	33.3

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