PDE8B (NM_003719) Human 3' UTR Clone

Specifications

Product Data
Product Name	PDE8B (NM_003719) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ADSD; PPNAD3
ACCN	NM_003719
Insert Size	1732 bp
Sequence Data	Insert Sequence (showhide) >SC210606 3’UTR clone of NM_003719 The sequence shown below is from the reference sequence of NM_003719. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAAAGTTTGAGGCTTCCATCTGACAGCTAAAGCCAAGCCACAGAGGGGGCCTCTTGACCGACAAAGGAC ACTGTGAATCACAGTAGCGTAAACGAGAGGCCTTCCTTTCTAATGACAATGACAGGTATTGGTGAAGGA GCTAATGTTTAATATTTGACCTTGAATCATTCAAGTCCCCAAATTTCATTCTTAGAAAGTTATGTTCCA TGAAGAAAAATATATGTTCTTTTGAATACTTAATGACAGAACAAATACTTGGCAAACTCCTTTGCTCTG CTGTCATCCTGTGTACCCTTGTCAATCCATGGAGCTGGTTCACTGTAACTAGCAGGCCACAGGAAGCAA AGCCTTGGTGCCTGTGAGCTCATCTCCCAGGATGGTGACTAAGTAGCTTAGCTAGTGATCAGCTCATCC TTTACCATAAAAGTCATCATTGCTGTTTAGCTTGACTGTTTTCCTCAAGAACATCGATCTGAAGGATTC ATAAGGAGCTTATCTGAACAGATTTATCTAAGAAAAAAAAAAAACGACATAAAATAAGTGAAACAACTA GGACCAAATTACAGATAAACTAGTTAGCTTCACAGCCTCTATGGCTACATGGTTCTTCTGGCCGATGGT ATGACACCTAAGTTAGAACACAGCCTTGGCTGGTGGGTGCCCTCTCTAGACTGGTATCAGCAGCCTGTG TAACCCCTTTCCTGTAAAAGGGGTTCATCTTAACAAAGTCATCCATGATGAGGGAAAAAGTGGCATTTC ATTTTTGGGGAATCCATGAGCTTCCTTTATTTCTGGCTCACAGAGGCAGCCACGAGGCACTACACCAAG TATTATATAAAAGCCATTAAATTTGAATGCCCTTGGACAAGCTTTTCTTAAAAAAAAAAAAAAAAAGTT TATATACATGTTTAAAATTTTTATTAAAATCCAAATTTTCTGGGTGTAAGCCCATGCAGTATGTTGTGC CATGCACCATCTATACGTAATATTTTGGGAGGGGATAGGGGAAGTTTCAAGGTTCAGATATTTTTAACC AGTCTATATTTGAAATCATGCCATTAGCTTTAACAATGTTAAAATTGTGTGGTGTAAATATATCAGAAA ATAGGCATATGGGGAGGCAGTAAATACTATTTTAAGCTATTAATTGTATGCTAAAAGCTTCTAAAGCAC AAGTGCATATTTTTATACTGCTCTTTTCACAACTCCCTGTGATCTACATAAAGTCAGACTCGAGATTTT CCTTTCTCTTTTACCAGCTGATCCTTCCTATGTATTATAAATATTAGACTCCGTAAACAAACTTCATTT TTCTTTCTCTGTACTTCATGCTGCATTTTTAAAAGGTATAAACAAACAGAGACTGAATTAATTGAATCA GTAATTACTTTTTTCCAATACAAATTGGAATGCAGAATACTTGGAACTTGTACATGGGGAAAAAATGAC TTATCACTACATAATGTGCCAATGTTTTTTTCTATGTTTTGTACCAAAAATGGAAAAATATGACAATTC CATGCAAAGAAATGTATCTAAATTATTTTTGTTAGATGATAAGAGAACTTGCTTGGTCAGGACAGCAGC CAGCTTTGTATTGTAATGCTATATTATGTAAATGTGATGAAAATGTTTTTGTGAAGTACTTGTAACTAA ATTCCTACAGCCATTTTTCACTCCCAACAGCTGTTTTTATTTTACCTCTTTGGCCTAAAGTTTTCATAA TTTCAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003719.5
Synonyms	ADSD; PPNAD3
Summary	The protein encoded by this gene is a cyclic nucleotide phosphodiesterase (PDE) that catalyzes the hydrolysis of the second messenger cAMP. The encoded protein, which does not hydrolyze cGMP, is resistant to several PDE inhibitors. Defects in this gene are a cause of autosomal dominant striatal degeneration (ADSD). Several transcript variants encoding different isoforms have been found for this gene.[provided by RefSeq, Jul 2010]
Locus ID	8622
MW	66.2

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