Bonzo (CXCR6) (NM_006564) Human 3' UTR Clone

Specifications

Product Data
Product Name	Bonzo (CXCR6) (NM_006564) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BONZO; CD186; CDw186; STRL33; TYMSTR
ACCN	NM_006564
Insert Size	871 bp
Sequence Data	Insert Sequence (showhide) >SC210387 3’UTR clone of NM_006564 The sequence shown below is from the reference sequence of NM_006564. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GTGGAGGCCACCAGCATGTTCCAGTTATAGGCCTTGCCAGGGTTTCGAGAAGCTGCTCTGGAATTTGCA AGTCATGGCTGTGCCCTCTTGATGTGGTGAGGCAGGCTTTGTTTATAGCTTGCGCATTCTCATGGAGAA GTTATCAGACACTCTGGCTGGTTTGGAATGCTTCTTCTCAGGCATGAACATGTACTGTTCTCTTCTTGA ACACTCATGCTGAAAGCCCAAGTAGGGGGTCTAAAATTTTTAAGGACTTTCCTTCCTCCATCTCCAAGA ATGCTGAAACCAAGGGGGATGACATGTGACTCCTATGATCTCAGGTTCTCCTTGATTGGGACTGGGGCT GAAGGTTGAAGAGGTGAGCACGGCCAACAAAGCTGTTGATGGTAGGTGGCACACTGGGTGCCCAAGCTC AGAAGGCTCTTCTGACTACTGGGCAAAGAGTGTAGATCAGAGCAGCAGTGAAAACAAGTGCTGGCACCA CCAGGCACCTCACAGAAATGAGATCAGGCTCTGCCTCACCTTGGGGCTTGACTTTTGTATAGGTAGATG TTCAGATTGCTTTGATTAATCCAGAATAACTAGCACCAGGGACTATGAATGGGCAAAACTGAATTATAA GAGGCTGATAATTCCAGTGGTCCATGGAATGCTTGAAAAATGTGCAAAACAGCGTTTAAGACTGTAATG AATCTAAGCAGCATTTCTGAAGTGGACTCTTTGGTGGCTTTGCATTTTAAAAATGAAATTTTCCAATGT CTGCCACACAAACGTATGTAAATGTATATACCCACACACATACACACATATGTCATATATTACTAGCAT ATGAGTTTCATAGCTAAGAAATAAAACTGTTAAAGTCTCCAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006564.2
Synonyms	BONZO; CD186; CDw186; STRL33; TYMSTR
Summary	The protein encoded by this gene is a G protein-coupled receptor with seven transmembrane domains that belongs to the CXC chemokine receptor family. This family also includes CXCR1, CXCR2, CXCR3, CXCR4, CXCR5, and CXCR7. This gene, which maps to the chemokine receptor gene cluster, is expressed in several T lymphocyte subsets and bone marrow stromal cells. The encoded protein and its exclusive ligand, chemokine ligand 16 (CCL16), are part of a signalling pathway that regulates T lymphocyte migration to various peripheral tissues (the liver, spleen red pulp, intestine, lungs, and skin) and promotes cell-cell interaction with dendritic cells and fibroblastic reticular cells. CXCR6/CCL16 also controls the localization of resident memory T lymphocytes to different compartments of the lung and maintains airway resident memory T lymphocytes, which are an important first line of defense against respiratory pathogens. The encoded protein serves as an entry coreceptor used by HIV-1 and SIV to enter target cells, in conjunction with CD4. [provided by RefSeq, Aug 2020]
Locus ID	10663
MW	33

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