DKC1 (NM_001363) Human 3' UTR Clone
CAT#: SC210345
3' UTR clone of dyskeratosis congenita 1 dyskerin (DKC1) transcript variant 1 for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
Cited in 1 publication. |
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经常一起买 (2)
Specifications
Product Data | |
Product Name | DKC1 (NM_001363) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | CBF5; DKC; DKCX; NAP57; NOLA4; XAP101 |
ACCN | NM_001363 |
Insert Size | 852 bp |
Sequence Data |
>SC210345 3’UTR clone of NM_001363
The sequence shown below is from the reference sequence of NM_001363. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GCAAAAGAGGTAGAATTGGTTTCTGAGTAGTGAAGGCCACTTGAAGCTGGAGGAGAAACTAAAGCCTTA TTGAGAAAACATGTTATAGATCCTTTTGTTGCTGAGAGAGTGGAACATAGGTCCTAGACAGGGTGAAGA GTTCTGGCACATTTTAGCTGCTACTTTGAGACCTCGGTGATGTTACCTGGTGTGGTCATCCCATCTTGT CCTGTTTTAAGGATATGGGTGGTGAAAGATGAAAGAGGCAGAGTTTATCCCAATGACTTCTCTGTTTGA GTTGGGAAGCCTCACCTTCAGACCCAGTAACTGTCCGCAGCTGTCTGCTAGTGGTTGTCTTAACATCGT AGTCCTAGTTTGCATTTTTTAAATCCCCTCTGTTTAAAAGGTTTGTAAAACAAAAACAAAAAACTAAGT CTGCTCAGTGAAATGCTGTAGAACCCTAAATAAGTGGTAGAAGAGTGTCACTGAATTTTGTCTCTGAAT TCAGTATAACTGAGTTTTGTCCATGCTGGTGTCTGGGTTATAGGCCTGATGGGCCTGGTAGTTTTCCAT CTTGTTCTGGCCTAGAGGTCAGTCCTTTGCACTTCCTCAAAGCTTGTGTACAGTGCTCACCTAAATCCA TCTGACTACTTGTTCCTGTGCCCTCTTGTTTTAGGCCTCGTTTACTTTTAAAAAATGAAATTGTTCATT GCTGGGAGAAGAATGTTGTAATTTTTACTTATTAAAGTCAACTTGTTAAGTTTTTTATGTATTCCTGTT GGGTTTTCTTGTTGATCTCATGCTAGCAGAGCAAAAATTGTAAAATATTTTGATTAAAAATCTAGGGAC CTTTATGTCCTATTTGAAATGTGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_001363.5 |
Synonyms | CBF5; DKC; DKCX; NAP57; NOLA4; XAP101 |
Summary | This gene functions in two distinct complexes. It plays an active role in telomerase stabilization and maintenance, as well as recognition of snoRNAs containing H/ACA sequences which provides stability during biogenesis and assembly into H/ACA small nucleolar RNA ribonucleoproteins (snoRNPs). This gene is highly conserved and widely expressed, and may play additional roles in nucleo-cytoplasmic shuttling, DNA damage response, and cell adhesion. Mutations have been associated with X-linked dyskeratosis congenita. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jan 2014] |
Locus ID | 1736 |
MW | 32 |
Citations (1)
The use of this cDNA Clones has been cited in the following citations: |
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Telomere elongation in induced pluripotent stem cells from dyskeratosis congenita patients
,null,
Nature
,PubMed ID 20164838
[DKC1]
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