LATS1 (NM_004690) Human 3' UTR Clone
CAT#: SC210118
3' UTR clone of LATS large tumor suppressor homolog 1 (Drosophila) (LATS1) for miRNA target validation
Need custom modification / cloning service?
Get a free quote
CNY 4,845.00
货期*
3周
规格
Product images
![](https://cdn.origene.com/img/defaults-img.jpg)
经常一起买 (2)
Specifications
Product Data | |
Product Name | LATS1 (NM_004690) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | WARTS; wts |
ACCN | NM_004690 |
Insert Size | 2000 bp |
Sequence Data |
>SC210118 3’UTR clone of NM_004690
The sequence shown below is from the reference sequence of NM_004690. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ATTAAAAATCGCGATCTAGTATATGTTTAACACACTAGTAAATAAATGTAATGAGGATTTGTAAAAGGG CCTGAAATGCGAGGTGTTTTGAGGTTCTGAGAGTAAAATTATGCAAATATGACAGAGCTATATATGTGT GCTCTGTGTACAATATTTTATTTTCCTAAATTATGGGAAATCCTTTTAAAATGTTAATTTATTCCAGCC GTTTAAATCAGTATTTAGAAAAAAATTGTTATAAGGAAAGTAAATTATGAACTGAATATTATAGTCAGT TCTTGGTACTTAAAGTACTTAAAATAAGTAGTGCTTTGTTTAAAAGGAGAAACCTGGTATCTATTTGTA TATATGCTAAATAATTTTAAAATACAAGAGTTTTTGAAATTTTTTTGAAAGACAGTTTTAGTTTTATCT TGCTTTAACCAAATATGAAACATACCCCCTATTTTACAGAGCTCTTTTTTCCCCTCATAACCTTGTTTT TGGTAGAAAATAAGCTAGAGAAATTAAGCCATCGTGTTGGTGAGTGTTCCTAGGCTAATGATAATCTGT ATAATTCACATCCTGAAACTAAGGAATACAGGGTTGAAAAAATATTAATATGTTTGTCAGAAGGAAAAA TAATGCATTTATCTTCCCCCCCACCCCCCGCCCCATGGAATATTTAATCTATTTAATCTTCTTGCATTT ATTTCTCAAGAATTACTGGCTTTAAAAGAAGCCAAAGCACTACTAGCTTTTTTTCCATATTGGTATTTT TGATGCTGCTTCCAATTTTAAAAGGGAACAAAGCTGCCATAAATCGAAATGTTCAATACTAAAAGCTAA AATATTTCTCACCATCCTAAGCAGATAATTATTTTAATTTTCATATACTTTTCCTGTATAGTAACTATT TTGATTATATCATCAATGTTACCTGTTTCCTCTTTCAGAACAGTGCTGCATATACAGATTGTTATTGGC AAAGGAAAATCTGGCTATCTGGCAATATTTTACCTAAGCGCAGATTAATTGGTGAAAAAATTAACTCTT AAGATGGCCATTAATAATTAGGAAAGTTTACAGAGTGGTCTTAGTAGAAAATTCAAGTCCTCCTAATTT ATTTAAGGTTCAATAATGCGTTCAACATGCCTGTTATGTATAACGCTTAGGTTCTAAGGAAGATTAAGG TTTCATACCAAAATACATGTAGCTTATCTTTTAGGAAGGGGAAAAAGGCTCCATTTTGACCATAGTAAA ATTTGTGTTGTGTTTTATTTCCTTTTCTTAAGCTCCACTGATAAGGGATTGTTTTTATCAAAAGTTACT ATTTGTAGATTGGAGGCATAATTTTAGTGATTTTCATACTTTTAGCTTTCTTCGCATAAAAGCTAATTG AAACCGTATATGTAGTAAAATTAAAGGCAGAGCTGTTGCAGTTGAATTGGAGAGTTAGGGCAAAGAACA CTTATTAGCCCACACTTCCCACCTTTCTACAGGTGGTCCTTTCAGAGCTCAGCCTGAAAACCCACTACT GTGTTATCGTGCGTCTTTTGGGGTTAGTGGTTCTTTTGAGAATCTGAAGGAAGCTGTGGACTCTTCCTA GAAAAAAAAACCACACATACACATACAATGTTGCATGCAGTTTCAAGGGATTTTGGACATATTGAAACC TATCACAGGCTGTAGGTTATGGACCTCTGTGCCATGAGAAAATTGATACATTAAACTAAGAACTTTGTT TTTAACTTACCAATCACTACTCAGCACATCTTATATAAGCTGATAATTTGTGATGGAAAAGGTCTGTAG CATGTGATATAAGGTGACCTTATGAATGCCTCTCTTGCTGGTACATTAAGTTGTTTTAATATATCATTT GGAGGGGACTGAAATGTTAGGCTCATTACAAGCTTGATACAGAAATATTTCTGAAGGATTTCTAATCAG AATTGTAAAACAATGTGCTATCATGAAATCGCAGTCTTCACCTCATGGTTCATGGAACATTTGGTTAG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_004690.4 |
Synonyms | WARTS; wts |
Summary | The protein encoded by this gene is a putative serine/threonine kinase that localizes to the mitotic apparatus and complexes with cell cycle controller CDC2 kinase in early mitosis. The protein is phosphorylated in a cell-cycle dependent manner, with late prophase phosphorylation remaining through metaphase. The N-terminal region of the protein binds CDC2 to form a complex showing reduced H1 histone kinase activity, indicating a role as a negative regulator of CDC2/cyclin A. In addition, the C-terminal kinase domain binds to its own N-terminal region, suggesting potential negative regulation through interference with complex formation via intramolecular binding. Biochemical and genetic data suggest a role as a tumor suppressor. This is supported by studies in knockout mice showing development of soft-tissue sarcomas, ovarian stromal cell tumors and a high sensitivity to carcinogenic treatments. [provided by RefSeq, Apr 2017] |
Locus ID | 9113 |
MW | 77.4 |
Documents
Product Manuals |
FAQs |
Resources
Customer
Reviews
Loading...