AMPK gamma 3 (PRKAG3) (NM_017431) Human 3' UTR Clone

Specifications

Product Data
Product Name	AMPK gamma 3 (PRKAG3) (NM_017431) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AMPKG3; SMGMQTL
ACCN	NM_017431
Insert Size	915 bp
Sequence Data	Insert Sequence (showhide) >SC210083 3’UTR clone of NM_017431 The sequence shown below is from the reference sequence of NM_017431. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCTGCTGGCATCGATGCCCTCGGGGCCTGAGAAGATCTGAGTCCTCAATCCCAAGCCACCTGCACACCT GGAAGCCAATGAAGGGAACTGGAGAACTCAGCCTTCATCTTCCCCCACCCCCATTTGCTGGTTCAGCTA TGATTCAGGCTTCTTCAGCCCTCCCAAATTGCCCTTGCCCTACCTGTGCTCCCAGAAGCCCTCGGGCAT GCCCAGTGCACCATGGGATGATGAAATTAAGGAGAACAGCTGAGTCAAGCTTGGAGGTCCCTGAACCAG AGGCACTAGGATTACCCCAGGGCCATCTGTGCTCCATGCCCGCCCATCCCCTTGCCGCCTGACTGGGTC GGATGGCCCCAGTGGGTTTAGTCAGGGCTTCTGGATTCCTCGGTTTCTGGGCTACCTATGGCTTCAGCC TTCAGCTCCTGGGAGTCCCAGCTGTTGTTCCCAGCAACGTCGCCACTGCCCTCCTACTCTCCAGGCTTT GTCATTTCAAGGCTGCTGAAATGCTGCATTTCAGGGGCCACCATGGAGCAGCCGTTATTTATAGAACTG CCTGTTGGAGGTGGGGAGTCCTCCCTCCATTCTTGTCCAGAAAACTCCTTAGCTCTCGCAGTGAGCCAT GTTCTTAGTCTCCAGGGATGGATGGCCTTGTATATGGACCCCTGAGAATGAGCAATTGAGAAAACAAAA CAAAAGGAACAATCCATGAACTTAGATTTTATTGGTTTCACTCAAAATGCTGCAGTCATTTGACCTGAA CTTGTGGCAAGAGACTTGTGCTTTCTAAATTCAAAGACTAGAAGGAAAATGGATAAAAATCACAAGTGC CGTTTCTCTTGCAATGTAGCGCTATTCTACTGAAATTTCTTTCTTCTCTTTTCTTTACAAAATCATAAA GAAAAAATTAATTCATTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_017431.4
Synonyms	AMPKG3; SMGMQTL
Summary	The protein encoded by this gene is a regulatory subunit of the AMP-activated protein kinase (AMPK). AMPK is a heterotrimer consisting of an alpha catalytic subunit, and non-catalytic beta and gamma subunits. AMPK is an important energy-sensing enzyme that monitors cellular energy status. In response to cellular metabolic stresses, AMPK is activated, and thus phosphorylates and inactivates acetyl-CoA carboxylase (ACC) and beta-hydroxy beta-methylglutaryl-CoA reductase (HMGCR), key enzymes involved in regulating de novo biosynthesis of fatty acid and cholesterol. This subunit is one of the gamma regulatory subunits of AMPK. It is dominantly expressed in skeletal muscle. Studies of the pig counterpart suggest that this subunit may play a key role in the regulation of energy metabolism in skeletal muscle. [provided by RefSeq, Jul 2008]
Locus ID	53632
MW	33.7

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