Ephexin 1 (NGEF) (NM_019850) Human 3' UTR Clone

Specifications

Product Data
Product Name	Ephexin 1 (NGEF) (NM_019850) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ARHGEF27; EPHEXIN
ACCN	NM_019850
Insert Size	818 bp
Sequence Data	Insert Sequence (showhide) >SC210034 3’UTR clone of NM_019850 The sequence shown below is from the reference sequence of NM_019850. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AGGAAGCTGGGCAGCCGGAATCGGCAATGACCCCCACCCAGGGGGCCAGCGGGAGCAGGGCCTGCATGA GACCCCGACAGAAGGTGGGGGGGGGGGGGCTCTGGGAAGCACAGGCCAGCACCTCCCCAGGTGGCAGGA TCTGGCTTGGGGTGCCCGGCCCTCATCCCTGCCCACGCAGTGAGTGCTCATGTGTCTTGGCCCCTTGCT CGCAAACTGGATAAAGGGTGCCCAAGCCTCTCCTGATGCATTTGTAAACAAGAAGGTTTCAGCAGTATT ACACCACCTCCCTCATGCCTCCGAGGGGGTGGAAGGGGGTGGGCACACTCCAGGGCCCCCCATGCCCCT GGCCCCCAGGGACTGGAAGAGGCTCCCAACCCAGAGTGTCCCTGTGGGAGGCAGGCAGAAGGTGACAAT TGACACGATTTCCTGCACGCGTCCTCCTCTACCTTGGAAGCAGTTAGAATCTACCAGGCACAGATGAGG CCGCCCTTGCCTGACGGAGCTTGATGAGCAGCCCTTGGTCTCCGGTTCCAGGACTGAGAGCCCAGCTGC CTCTGCCCACCCTTCCCCAGGCCTCTGCCAGCCTCTGGCTGCACGGTCAGGCCCTGCCCCATGGCAGGC CTGCCAGAGCTTGGCTGGGGACCCCTCCCGCCTCTGGCTCCCTGATGGGCTGGATGTAACTTGTGTCTT CTAGCCCCTTAAGGAGCCCAGGTGTTTTAAGGAATGAATTGGTCACTGCATCTTGTATCGATTATGGTT CTGAGAAAAGCAAATATCACTTTTGGCTGCATTAAAAGAAGCATCATATATAAAATAAA AGCGGACCGACTTACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCC CAACCTGCCATCACGAGATTTCGATTCCACCGCCGC
Restriction Sites	SgfI-RsrII
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_019850.3
Synonyms	ARHGEF27; EPHEXIN
Summary	Acts as a guanine nucleotide exchange factor (GEF) which differentially activates the GTPases RHOA, RAC1 and CDC42. Plays a role in axon guidance regulating ephrin-induced growth cone collapse and dendritic spine morphogenesis. Upon activation by ephrin through EPHA4, the GEF activity switches toward RHOA resulting in its activation. Activated RHOA promotes cone retraction at the expense of RAC1- and CDC42-stimulated growth cone extension (By similarity).[UniProtKB/Swiss-Prot Function]
Locus ID	25791
MW	28.7

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