SPRY2 (NM_005842) Human 3' UTR Clone

Specifications

Product Data
Product Name	SPRY2 (NM_005842) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	hSPRY2; IGAN3
ACCN	NM_005842
Insert Size	812 bp
Sequence Data	Insert Sequence (showhide) >SC209982 3’UTR clone of NM_005842 The sequence shown below is from the reference sequence of NM_005842. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCCCCTAGGAACTTTGAAAAACCAACATAGCATCATTAATCAGGAATATTACAGTAATGAGGATTTTTT CTTTCTTTTTTTAATACACATATGCAACCAACTAAACAGTTATAATCTTGGCACTGTTAATAGAAAGGT GGGATAGTCTTTGCTGTTTGCGGTGAAATGCTTTTTGTCCATGTGCCGTTTTAACTGATATGCTTGTTA GAACTCAGCTAATGGAGCTCAAAGTATGAGATACAGAACTTGGTGACCCATGTATTGCATAAGCTAAAG CAACACAGACACTCCTAGGCAAAGTTTTTGTTTGTGAATAGTACTTGCAAAACTTGTAAATTAGCAGAT GACTTTTTTCCATTGTTTTCTCCAGAGAGAATGTGCTATATTTTTGTATATACAATAATATTTGCAACT GTGAAAAACAAGTTGTGCCATACTACATGGCACAGACACAAAATATTATACTAATATGTTGTACATTCG GAAGAATGTGAATCAATCAGTATGTTTTTAGATTGTATTTTGCCTTACAGAAAGCCTTTATTGTAAGAC TCTGATTTCCCTTTGGACTTCATGTATATTGTACAGTTACAGTAAAATTCAACCTTTATTTTCTAATTT TTTCAACATATTGTTTAGTGTAAAGAATATTTATTTGAAGTTTTATTATTTTATAAAAAAGAATATTTA TTTTAAGAGGCATCTTACAAATTTTGCCCCTTTTATGAGGATGTGATAGTTGCTGCAAATGAGGGGTTA CAGATGCATATGTCCAATATAAAATAGAAAATATATTAACGTTTGAAATTAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_005842.4
Synonyms	hSPRY2; IGAN3
Summary	This gene encodes a protein belonging to the sprouty family. The encoded protein contains a carboxyl-terminal cysteine-rich domain essential for the inhibitory activity on receptor tyrosine kinase signaling proteins and is required for growth factor stimulated translocation of the protein to membrane ruffles. In primary dermal endothelial cells this gene is transiently upregulated in response to fibroblast growth factor two. This protein is indirectly involved in the non-cell autonomous inhibitory effect on fibroblast growth factor two signaling. The protein interacts with Cas-Br-M (murine) ectropic retroviral transforming sequence, and can function as a bimodal regulator of epidermal growth factor receptor/mitogen-activated protein kinase signaling. This protein may play a role in alveoli branching during lung development as shown by a similar mouse protein. [provided by RefSeq, Jul 2008]
Locus ID	10253
MW	32.2

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