MCSF Receptor (CSF1R) (NM_005211) Human 3' UTR Clone

Specifications

Product Data
Product Name	MCSF Receptor (CSF1R) (NM_005211) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BANDDOS; C-FMS; CD115; CSF-1R; CSFR; FIM2; FMS; HDLS; M-CSF-R
ACCN	NM_005211
Insert Size	804 bp
Sequence Data	Insert Sequence (showhide) >SC209962 3’UTR clone of NM_005211 The sequence shown below is from the reference sequence of NM_005211. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CTGCAGCCCAACAACTATCAGTTCTGCTGAGGAGTTGACGACAGGGAGTACCACTCTCCCCTCCCACAA ACTTCAACTCCTCCATGGATGGGGCGACACGGGGAGAACATACAAACTCTGCCTTCGGTCATTTCACTC AACAGCTCGGCCCAGCTCTGAAACTTGGGAAGGTGAGGGATTCAGGGGAGGTCAGAGGATCCCACTTCC TGAGCATGGGCCATCACTGCCAGTCAGGGGCTGGGGGCTGAGCCCTCACCCCCCCCTCCCCTACTGTTC TCATGGTGTTGGCCTCGTGTTTGCTATGCCAACTAGTAGAACCTTCTTTCCTAATCCCCTTATCTTCAT GGAAATGGACTGACTTTATGCCTATGAAGTCCCCAGGAGCTACACTGATACTGAGAAAACCAGGCTCTT TGGGGCTAGACAGACTGGCAGAGAGTGAGATCTCCCTCTCTGAGAGGAGCAGCAGATGCTCACAGACCA CACTCAGCTCAGGCCCCTTGGAGCAGGATGGCTCCTCTAAGAATCTCACAGGACCTCTTAGTCTCTGCC CTATACGCCGCCTTCACTCCACAGCCTCACCCCTCCCACCCCCATACTGGTACTGCTGTAATGAGCCAA GTGGCAGCTAAAAGTTGGGGGTGTTCTGCCCAGTCCCGTCATTCTGGGCTAGAAGGCAGGGGACCTTGG CATGTGGCTGGCCACACCAAGCAGGAAGCACAAACTCCCCCAAGCTGACTCATCCTAACTAACAGTCAC GCCGTGGGATGTCTCTGTCCACATTAAACTAACAGCATTAATGCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_005211.4
Synonyms	BANDDOS; C-FMS; CD115; CSF-1R; CSFR; FIM2; FMS; HDLS; M-CSF-R
Summary	The protein encoded by this gene is the receptor for colony stimulating factor 1, a cytokine which controls the production, differentiation, and function of macrophages. This receptor mediates most if not all of the biological effects of this cytokine. Ligand binding activates the receptor kinase through a process of oligomerization and transphosphorylation. The encoded protein is a tyrosine kinase transmembrane receptor and member of the CSF1/PDGF receptor family of tyrosine-protein kinases. Mutations in this gene have been associated with a predisposition to myeloid malignancy. The first intron of this gene contains a transcriptionally inactive ribosomal protein L7 processed pseudogene oriented in the opposite direction. Alternative splicing results in multiple transcript variants. Expression of a splice variant from an LTR promoter has been found in Hodgkin lymphoma (HL), HL cell lines and anaplastic large cell lymphoma. [provided by RefSeq, Mar 2017]
Locus ID	1436
MW	29.2

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