TEA domain family member 2 (TEAD2) (NM_003598) Human 3' UTR Clone

Specifications

Product Data
Product Name	TEA domain family member 2 (TEAD2) (NM_003598) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ETF; TEAD-2; TEF-4; TEF4
ACCN	NM_003598
Insert Size	759 bp
Sequence Data	Insert Sequence (showhide) >SC209845 3’UTR clone of NM_003598 The sequence shown below is from the reference sequence of NM_003598. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CATCACATTTACCGCCTGGTCAGGGACTGAAGGGGGACCCCAAAACTGGCTCACCCCCCAGAACACCCT CCTCCCAGGGAGGGTCCTCCAGCTCACCTCATGCTTCTTATTTGGGGAGAGGGCTGTGATGTAAAGGGG TTGACCTCAGAGGCCTAAGCAACTGGGGCCATCCCCCCCATTAGAGGGGCCCCCAAAACTTGGTTGGAG AGCTGAACAGGCTGGGACTGAGGAAAGGATAAACCCCGATATTGGGACCTCACAGTGGGTGTCTGAAAG GACAGATCACTCCGGAGTATCAGGGATTGTGGGGACAGGAGTGAGACAACCCCCCAGGTACAGCACTGG CTTTTCTTTTCAGCCCCTGACAGGCCACCCCCACTCCTCTGCATGTCTTGGAGAGCGCTAGTTACACAT TGGCTTGTCCCCTTTACTTTTTCCCAGCCACCCCTCCCCCTGAAATTTCTGCCCCTCTCTACCACCCTC ACTCCATGACCTGTGAGATCACAAAGTGAAGATGAACCCTTTCTGTGCAGGAGCAGAGCCAGGTGGGCC CTGGACATTTTTTTTTTTTTTAATATAACGAGATATTTATAAGTGGGTGCTAGGGTCTTGACTTTATCT CCGCTGCACAAGCAGTGTGTTGAACTTTCTAATCTCATCCCTCTCCTAAGTGAGCCCTGAGCTAGACGG TTTCCTTCCTCCCCTCTCAAAGTTTGTTTGTTTGTGTTCTGACAGAGGATAAAGCTATTTTACCAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003598.2
Synonyms	ETF; TEAD-2; TEF-4; TEF4
Summary	Transcription factor which plays a key role in the Hippo signaling pathway, a pathway involved in organ size control and tumor suppression by restricting proliferation and promoting apoptosis. The core of this pathway is composed of a kinase cascade wherein MST1/MST2, in complex with its regulatory protein SAV1, phosphorylates and activates LATS1/2 in complex with its regulatory protein MOB1, which in turn phosphorylates and inactivates YAP1 oncoprotein and WWTR1/TAZ. Acts by mediating gene expression of YAP1 and WWTR1/TAZ, thereby regulating cell proliferation, migration and epithelial mesenchymal transition (EMT) induction. Binds to the SPH and GT-IIC 'enhansons' (5'-GTGGAATGT-3'). May be involved in the gene regulation of neural development. Binds to the M-CAT motif.[UniProtKB/Swiss-Prot Function]
Locus ID	8463
MW	29

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.