FLT3 (NM_004119) Human 3' UTR Clone

Specifications

Product Data
Product Name	FLT3 (NM_004119) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CD135; FLK-2; FLK2; STK1
ACCN	NM_004119
Insert Size	808 bp
Sequence Data	Insert Sequence (showhide) >SC209844 3’UTR clone of NM_004119 The sequence shown below is from the reference sequence of NM_004119. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCTCCGCAGGCTCAGGTCGAAGATTCGTAGAGGAACAATTTAGTTTTAAGGACTTCATCCCTCCACCTA TCCCTAACAGGCTGTAGATTACCAAAACAAGATTAATTTCATCACTAAAAGAAAATCTATTATCAACTG CTGCTTCACCAGACTTTTCTCTAGAAGCTGTCTGCGTTTACTCTTGTTTTCAAAGGGACTTTTGTAAAA TCAAATCATCCTGTCACAAGGCAGGAGGAGCTGATAATGAACTTTATTGGAGCATTGATCTGCATCCAA GGCCTTCTCAGGCTGGCTTGAGTGAATTGTGTACCTGAAGTACAGTATATTCTTGTAAATACATAAAAC AAAAGCATTTTGCTAAGGAGAAGCTAATATGATTTTTTAAGTCTATGTTTTAAAATAATATGTAAATTT TTCAGCTATTTAGTGATATATTTTATGGGTGGGAATAAAATTTCTACTACAGAATTGCCCATTATTGAA TTATTTACATGGTATAATTAGGGCAAGTCTTAACTGGAGTTCACGAACCCCCTGAAATTGTGCACCCAT AGCCACCTACACATTCCTTCCAGAGCACGTGTGCTTTTACCCCAAGATACAAGGAATGTGTAGGCAGCT ATGGTTGTCACAGCCTAAGATTTCTGCAACAACAGGGGTTGTATTGGGGGAAGTTTATAATGAATAGGT GTTCTACCATAAAGAGTAATACATCACCTAGACACTTTGGCGGCCTTCCCAGACTCAGGGCCAGTCAGA AGTAACATGGAGGATTAGTATTTTCAATAAAGTTACTCTTGTCCCCACA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004119.3
Synonyms	CD135; FLK-2; FLK2; STK1
Summary	This gene encodes a class III receptor tyrosine kinase that regulates hematopoiesis. This receptor is activated by binding of the fms-related tyrosine kinase 3 ligand to the extracellular domain, which induces homodimer formation in the plasma membrane leading to autophosphorylation of the receptor. The activated receptor kinase subsequently phosphorylates and activates multiple cytoplasmic effector molecules in pathways involved in apoptosis, proliferation, and differentiation of hematopoietic cells in bone marrow. Mutations that result in the constitutive activation of this receptor result in acute myeloid leukemia and acute lymphoblastic leukemia. [provided by RefSeq, Jan 2015]
Locus ID	2322
MW	30.7

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.