Selenophosphate synthetase 2 (SEPHS2) (NM_012248) Human 3' UTR Clone

Specifications

Product Data
Product Name	Selenophosphate synthetase 2 (SEPHS2) (NM_012248) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	SPS2
ACCN	NM_012248
Insert Size	780 bp
Sequence Data	Insert Sequence (showhide) >SC209703 3’UTR clone of NM_012248 The sequence shown below is from the reference sequence of NM_012248. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCAAATGCCTCCTCTGAGCCTAGCTCGTGAGATGAAAGAACAGAAGTTGTTTGGACCTTAGAGCCATTG TCCACAATCACGGATGGTTCTCAAGAGTTGATTGTAAGAAATTTCCAAAGAAGGCTGCCTGCATAGTGG TTCCGGCTGCCCTTTCTAGGTGATTGGAATCAGCCCATCTAAAGCAGTCTTTATATGCATTCCGAGGCC AGAGTAACATTTTGAACTTTGGGGGGATATTTGTTCATCACTTGGGTAGAAGAGGAGCAAAAATACCTC TGTTTTCTCTTGCCAAAGTAAGATGAAGCTATTCCAGGTTGAGGGATTTTTCTTTGCACGGGGTTGATT AATTTCTGCACAGGGAGTGAGATTATTAAAGTAACACACACACAAAGTAAATTGCAAAATGAAAAAAAT TAGAAGCAAATGAGTTTTGGACCAATATTGTTGATAAATCTAAATTGTTAAGAGAGATCTTATAATGCA ACATCAAATTCTTTATTCAATTTTACTGAAGTACTGGCTCTTTCCTGCTCTGGACAAGAATTGAGCAAC TTGTCTGATGACTGGGAAAGGAGGACCTGCAACCATCTGACTTGGTCTCTGTTAATGACGTCTCTCCCT CTAAACCCCATTAAGGACTGGGAGAGGCAGAGCAAGCCTCAGAGCCCAGGCCTCAGTGGTCATTAAGAT GTTAAGTCTTTTGCGGCAGATTCCTGGTGATTTGATCAATAAAGAGTAATTTCTTGCTAAATAAATAAA AGAAACCTTGTTGAAAAACTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_012248.4
Synonyms	SPS2
Summary	This gene encodes an enzyme that catalyzes the production of monoselenophosphate (MSP) from selenide and ATP. MSP is the selenium donor required for synthesis of selenocysteine (Sec), which is co-translationally incorporated into selenoproteins at in-frame UGA codons that normally signal translation termination. The 3' UTRs of selenoprotein mRNAs contain a conserved stem-loop structure, the Sec insertion sequence (SECIS) element, which is necessary for the recognition of UGA as a Sec codon rather than as a stop signal. This protein is itself a selenoprotein containing a Sec residue at its active site, suggesting the existence of an autoregulatory mechanism. It is preferentially expressed in tissues implicated in the synthesis of selenoproteins and in sites of blood cell development. A pseudogene for this locus has been identified on chromosome 5. [provided by RefSeq, May 2017]
Locus ID	22928
MW	29.7

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