KDEL Receptor (KDELR1) (NM_006801) Human 3' UTR Clone

Specifications

Product Data
Product Name	KDEL Receptor (KDELR1) (NM_006801) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ERD2; ERD2.1; HDEL; PM23
ACCN	NM_006801
Insert Size	748 bp
Sequence Data	Insert Sequence (showhide) >SC209443 3’UTR clone of NM_006801 The sequence shown below is from the reference sequence of NM_006801. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAGGGGAAGAAGTTGAGTTTGCCGGCATAGCCCCGGTCCTCTCCATCTCTCTCCTCGGCAGCAGCGGGA GGCAGAGGAAGGCGGCAGAAGATGAAGAGCTTTCCCATCCAGGGGTGACTTTTTTAAGAACCCACCTCT TGTGCTCCCCATCCCGCCTCCTGCCGGGTTTCAGGGGGACAGTGGAGGATCCAGGTCTTGGGGAGCTCA GGACTTGGGCTGTTTGTAGTTTTTTGCCTTTTAGACAAGAAAAAAAAATCTTTCCACTCTTTAGTTTTT GATTCTGATGACTCGTTTTTCTTCTACTCTGTGGCCCCAATTTTTATAAAGTGTTTTTGAGTGTCCTAT GGGCCGGGGCAGGGTCCAAGATCTTTTCCCTTCCCCAGGCCCCTCGGCTCCCTCCCAGATCCCACCCCC AGCCCCACTGGTTGCCAAACACTAAATCTGCCGACACCCATCTGCCCCACCTCCTGCCATGGCCATGAA CCGCGACCCCCACTAAATTTCTAGATTGGGGATAGGGAGAAAGGGAGGCCCAGGAAGGTCTCCCCTGAT TTTTTTTCATAGTAATTTTTTTCCCCAGAGTTTGAATTTTTTGGTCTTCTCCTGGTTTTTTGGCAAATT AGGGGGGCCCGGGGCTCAAGTGCGGGAAGGGGGCTGGCCCGAGGATCCCATGGCTCTCACACCATGTTT TTGTACAGAACTGATGGTTGAATCTTTGTTCTCTTGAAATAAACAGAAGAAAATGAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_006801.3
Synonyms	ERD2; ERD2.1; HDEL; PM23
Summary	Retention of resident soluble proteins in the lumen of the endoplasmic reticulum (ER) is achieved in both yeast and animal cells by their continual retrieval from the cis-Golgi, or a pre-Golgi compartment. Sorting of these proteins is dependent on a C-terminal tetrapeptide signal, usually lys-asp-glu-leu (KDEL) in animal cells, and his-asp-glu-leu (HDEL) in S. cerevisiae. This process is mediated by a receptor that recognizes, and binds the tetrapeptide-containing protein, and returns it to the ER. In yeast, the sorting receptor encoded by a single gene, ERD2, which is a seven-transmembrane protein. Unlike yeast, several human homologs of the ERD2 gene, constituting the KDEL receptor gene family, have been described. The protein encoded by this gene was the first member of the family to be identified, and it encodes a protein structurally and functionally similar to the yeast ERD2 gene product. [provided by RefSeq, Jul 2008]
Locus ID	10945
MW	27.3

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