B4GALT3 (B4GALT2) (NM_001005417) Human 3' UTR Clone

Specifications

Product Data
Product Name	B4GALT3 (B4GALT2) (NM_001005417) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	B4Gal-T2; B4Gal-T3; beta4Gal-T2
ACCN	NM_001005417
Insert Size	758 bp
Sequence Data	Insert Sequence (showhide) >SC209406 3’UTR clone of NM_001005417 The sequence shown below is from the reference sequence of NM_001005417. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CGGCCTCCGTCGTGGCCCCCTCGGGGCTGACACTAATGGACAGAGGCTCTCGGTGCCGAAGATTGCCTG CCAGAGGACTGACCACAGCCTGGCTGGCAGCTGCTCTGTGGAGGACCTCCAGGACTGAGACTGGGCTCT GTTTTCCAAGGGTCTTCACTAGGCCCCCTAGCTACACCTGGAAGTTTCAGAACCCACTTTGGGGGGCCT CCTGCCTGGGCAGGCTCTTCAAGTGTGGCCCTCTTTGGAGTCAACCCTCCTTCCCGACCCCCTCCCCCT AGCCCAGCCCCAGTCACTGTCAGGGTCGGGCCAGCCCCTGCACTGCCTCGCAGAGTGGCCTGGGCTAGG TCACTCCACCTCTCTGTGCCTCAGTTTCCCCCCCTTGAGTCCCCTAGGGCCTGGAAGGGTGGGAGGTAT GTCTAGGGGGCAGTGTCTCTTCCAGGGGGAATTCTCAGCTCTTGGGAACCCCCTTGCTCCCAGGGGAGG GGAAACCTTTTTCATTCAACATTGTAGGGGGCAAGCTTTGGTGCGCCCCCTGCTGAGGAGCAGCCCCAG GAGGGGACCAGAGGGGATGCTGTGTCGCTGCCTGGGATCTTGGGGTTGGCCTTTGCATGGGAGGCAGGT GGGGCTTGGATCAGTAAGTCTGGTTCCCGCCTCCCTGTCTGAGAGAGGAGGCAGGAGCCCCAGGGCCGG CTTGTGTTTGTACATTGCACAGAAACTTGTGTGGGTGCTTTAGTAAAAAACGTGAATGGAGCAAAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001005417.2
Synonyms	B4Gal-T2; B4Gal-T3; beta4Gal-T2
Summary	This gene is one of seven beta-1,4-galactosyltransferase (beta4GalT) genes. They encode type II membrane-bound glycoproteins that appear to have exclusive specificity for the donor substrate UDP-galactose; all transfer galactose in a beta1,4 linkage to similar acceptor sugars: GlcNAc, Glc, and Xyl. Each beta4GalT has a distinct function in the biosynthesis of different glycoconjugates and saccharide structures. As type II membrane proteins, they have an N-terminal hydrophobic signal sequence that directs the protein to the Golgi apparatus and which then remains uncleaved to function as a transmembrane anchor. By sequence similarity, the beta4GalTs form four groups: beta4GalT1 and beta4GalT2, beta4GalT3 and beta4GalT4, beta4GalT5 and beta4GalT6, and beta4GalT7. The enzyme encoded by this gene synthesizes N-acetyllactosamine in glycolipids and glycoproteins. Its substrate specificity is affected by alpha-lactalbumin but it is not expressed in lactating mammary tissue. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Jul 2011]
Locus ID	8704
MW	26.4

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