PKR (EIF2AK2) (NM_001135652) Human 3' UTR Clone

Specifications

Product Data
Product Name	PKR (EIF2AK2) (NM_001135652) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	EIF2AK1; LEUDEN; PKR; PPP1R83; PRKR
ACCN	NM_001135652
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC209229 3’UTR clone of NM_001135652 The sequence shown below is from the reference sequence of NM_001135652. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCAGAGAAAAATGAACGACACACATGTTAGAGCCCTTCTGAAAAAGTATCCTGCTTCTGATATGCAGTT TTCCTTAAATTATCTAAAATCTGCTAGGGAATATCAATAGATATTTACCTTTTATTTTAATGTTTCCTT TAATTTTTTACTATTTTTACTAATCTTTCTGCAGAAACAGAAAGGTTTTCTTCTTTTTGCTTCAAAAAC ATTCTTACATTTTACTTTTTCCTGGCTCATCTCTTTATTCTTTTTTTTTTTTTAAAGACAGAGTCTCGC TCTGTTGCCCAGGCTGGAGTGCAATGACACAGTCTTGGCTCACTGCAACTTCTGCCTCTTGGGTTCAAG TGATTCTCCTGCCTCAGCCTCCTGAGTAGCTGGATTACAGGCATGTGCCACCCACCCAACTAATTTTTG TGTTTTTAATAAAGACAGGGTTTCACCATGTTGGCCAGGCTGGTCTCAAACTCCTGACCTCAAGTAATC CACCTGCCTCGGCCTCCCAAAGTGCTGGGATTACAGGGATGAGCCACCGCGCCCAGCCTCATCTCTTTG TTCTAAAGATGGAAAAACCACCCCCAAATTTTCTTTTTATACTATTAATGAATCAATCAATTCATATCT ATTTATTAAATTTCTACCGCTTTTAGGCCAAAAAAATGTAAGATCGTTCTCTGCCTCACATAGCTTACA AGCCAGCTGGAGAAATATGGTACTCATTAAAAAAAAAAAAAAAAGTGATGTACAACCACTTCGGAAAAC AATTTGGCATTATCTAGTAAAGTTGAATCCATGTATACCCACATAGCTATCAATTCTATTCCTACATAC GTGCTTACAAGAATGTCCATAAAACCCTGTTTATAATAGCCAAAAGAACAGGGAACAACCATAATGCAC ATCAAAAGAAGAATGGATTAAAAAAATTATATTCACACACAGGAGTACTATATAGTATTGAAAACAATT GAAGTACAGCTAAATGTAATAACGTAACACAATACAACTCTCAGAAACATAATGTTAAGCGAACAAAGC AGGTTTTCAGAAAATATATGCAGAATAATTCCATTTATATAAAGTTCCAGAGCATGCAAAACTAAATCA TTTTGTATAAAAAACCCAACAAATGTGATGAGACAATAATGGGAAGGAAGGGAATGAGAAATATTAAAT TCTGGATGGTGGTTATCTTTGAGGGAGGGGAATGATGTGATTGGGGAAATGGACTTTCAAAGGTAATGG TAACTTCCTTAAGCTGGATGGTAGGTCCACTAGTGTTTGCTGCATAGTTATACCTTTTATCTTAAATAC ATTTTGTATCTATTGTAACAACCACTTTAAAGACAACCGTGCTGTAAGGCAGTAGCTAAAAACAGAAAA TAGTCCATCGGGAAGGGTAAGATGGCTTTCTGCTGAGCACAGGGCTAGAAGTGACAGCCCAGTGGGCCT TCCAACTATATGCCAGGGTGTTAGATGAGTAGAGAGGAGACCACCCAGGAAGTCTGGACAAGGGGTCTG GCATGAGCTCTGGAGAAGATATATTTGAGGAACATGGGGTATGCTAGTTTGTTGTCCTGAATTGCTGTA GAGAAGATAATTTAAATTGCATCTTAGAAGACGACCCTGAGGGTGAATTTCAACTTAGGGCAATTGTTT TAGTTTGTTTCTTATTGGTTTAAATGGATACTTGAAGCTGGATAATTTATAAGGAAAAGAGATTTATAT GACTTACAGTTCTGCAGGCTGTACAAGAAACATGGCACCAGCATCTGCTTCTTCCCCGGCTGCTTCCAC TCATGGTGGAAGGTGAAGGGGAGCCGGATGTGCAGAGATCATATGGCAAGAGAGGAAGCAAGAGAGCGA GGGAGAAGGTGCCAGGCTCTTTTTAAATAACCGGCTCTTGAGGGAACTAATAGATTGAGAACTCCTTGC TTCTCCTCCCCAGCACACCCCACCCCCAGGGACGGCATTAATGTATTCATGAGGGGTCTTCCCCCATG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001135652.2
Synonyms	EIF2AK1; LEUDEN; PKR; PPP1R83; PRKR
Summary	The protein encoded by this gene is a serine/threonine protein kinase that is activated by autophosphorylation after binding to dsRNA. The activated form of the encoded protein can phosphorylate translation initiation factor EIF2S1, which in turn inhibits protein synthesis. This protein is also activated by manganese ions and heparin. Three transcript variants encoding two different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
Locus ID	5610
MW	77.2

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