MVK (NM_000431) Human 3' UTR Clone

Specifications

Product Data
Product Name	MVK (NM_000431) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	LRBP; MK; MVLK; POROK3
ACCN	NM_000431
Insert Size	1578 bp
Sequence Data	Insert Sequence (showhide) >SC209093 3’UTR clone of NM_000431 The sequence shown below is from the reference sequence of NM_000431. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CGAGTCCAGCAAGCCCTGGATGGCCTCTGAGAGGAGCCCACGACACTGCAGCCCCACCCAGATGCCCCT TTCTGGATTATTCTGGGGGCTGCAGTTCGACTCTGTGCTGGCCAGCGAGCGCCCAGCTCCTGACACTGC TGGAGAGGCCCCAGCCGCTTGGCGATGCCAGCCAAGCTCTGCAGTCCCAGCGGTGGGACCTAGGGAGGC ATGGTCTGCCCTCTGCATCCTCTGGAGCCAGCCGAGCAGGAGGCCTAGGAGGGTCCTCTGAGACTCCAG ACCTGAGGCGAGAAGGGCTGCTTCCCTGAAGCTCCCACAGTCCCATCTGCTTCAGGCCCCCGCCTTGGC CTGTGTTCTTCCTGGCCGCCTGGGTCCAATGCTCAGGTGCTGGGGCCTGGTTCCCGGAGAAGTGTGCCT TCTCTCTCCCTTTTCAGGGACCGCCCCCTGTCTCTCAGGGCCAGGCCTCTCCCTCCTCCAGGAAGCCTT CCCCTACCCCTTGTCGCCCCTCCCTCCCAGAGCACCTGCTGTCTGGGTGGCTCACTCAGCACTTGGTGT GGCCTTCCCTTCTACCTAGCGGGATGGGGCTCCCCCAGGGGCTGTCCCGGAGGCGGTGGGCCTGGTTAA ATAAGGCAGGGTTTATATGCACTTTCTTCCGATCTGTACCTGAGAGGTTTGTGGAAAAGATGGCAAATG GGGAATAAAAAGATTTTGTGTCAACAGTAGAGACTCCAGGCCACCAGCACCTCCCTCTGTCCCTGTCCC CTCTCCAGCTGTTTCCTCCATGGAGCTCTTCAGCAATGGAGGGAAATAGGGTTTGGGGTCACTTTGTTG TGCGTCTTGGGGATGAGGTGGCTTTTCCCAGATGGCCCTTGCTGGAGAGGGACTGGGACACGGCTCTCA GTCCATCAGCACAACTCTAGGCTGCTGCTGCGGAGGGAGAAGTTGAGCTTCCTAGCTCCAGAATCACAA GCACCCACGAGAGCACAGACCTGTGTAAGACAGGAAAGCAGAACCTGCCATCGCTCCTGGGGCGCGCCT TCCTTTCTGAAATGAACTGGCTGGATGGAGAAAACAGACTCAAATGTTCTGGCCCGGGTGCCTGGCACT CCCCACCCCCGCCCCCCACCGGCCCTATTTGAACTTTATATTGCAGTCAGCTTGGTGCTTTCCGAAATG CCATTAGCCATCAGGAAACCCTTGTAGTTGGTGCCTTGCCAGCCAGAACCTCTGGGACCCACGGACCTG CAAAGAGGCCGAGTGGAAAGGTGGGGGCCGGCGCAGGGATTTCAGGATGAGGTGAAAGCGATTCAGTGC GCGTCTGCCCTTGGCCACTAGGGGGCAGCTGGCGGCCTTCCCTGCTGTTGTCTTCCTGCAGGGTGAGAG GAGCAGGAGCCGAGCTCCACCCCCACGCCAGCCTTGGGCCCGGCCTGGGATCACTGCTGGGAACGTGAG AGTGAAGGGAGGACGCCTACCCCAGCTTAACTTGTAGAAATGGCCCCAGATCACTGATGGCTGTTCCCT GCCCCTTCCCTTCAAAACACAACGCATAAAGCAGTAATACTAATTAATACTGAACGCTCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000431.4
Synonyms	LRBP; MK; MVLK; POROK3
Summary	This gene encodes the peroxisomal enzyme mevalonate kinase. Mevalonate is a key intermediate, and mevalonate kinase a key early enzyme, in isoprenoid and sterol synthesis. Mevalonate kinase deficiency caused by mutation of this gene results in mevalonic aciduria, a disease characterized psychomotor retardation, failure to thrive, hepatosplenomegaly, anemia and recurrent febrile crises. Defects in this gene also cause hyperimmunoglobulinaemia D and periodic fever syndrome, a disorder characterized by recurrent episodes of fever associated with lymphadenopathy, arthralgia, gastrointestinal dismay and skin rash. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Jul 2014]
Locus ID	4598
MW	56.9

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