CSK (NM_001127190) Human 3' UTR Clone

Specifications

Product Data
Product Name	CSK (NM_001127190) Human 3' UTR Clone
Vector	pMirTarget
ACCN	NM_001127190
Insert Size	714 bp
Sequence Data	Insert Sequence (showhide) >SC209062 3’UTR clone of NM_001127190 The sequence shown below is from the reference sequence of NM_001127190. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CACATCAAAACCCACGAGCTGCACCTGTGACGGCTGGCCTCCGCCTGGGTCATGGGCCTGTGGGGACTG AACCTGGAAGATCATGGACCTGGTGCCCCTGCTCACTGGGCCCGAGCCTGAACTGAGCCCCAGCGGGCT GGCGGGCCTTTTTCCTGCGTCCCAGCCTGCACCCCTCCGGCCCCGTCTCTCTTGGACCCACCTGTGGGG CCTGGGGAGCCCACTGAGGGGCCAGGGAGGAAGGAGGCCACGGAGCGGGAGGCAGCGCCCCACCACGTC GGGCTTCCCTGGCCTCCCGCCACTCGCCTTCTTAGAGTTTTATTCCTTTCCTTTTTTGAGATTTTTTTT CCGTGTGTTTATTTTTTATTATTTTTCAAGATAAGGAGAAAGAAAGTACCCAGCAAATGGGCATTTTAC AAGAAGTACGAATCTTATTTTTCCTGTCCTGCCCGTGAGGGTGGGGGGGACCGGGCCCCTCTCTAGGGA CCCCTCGCCCCAGCCTCATTCCCCATTCTGTGTCCCATGTCCCGTGTCTCCTCGGTCGCCCCGTGTTTG CGCTTGACCATGTTGCACTGTTTGCATGCGCCCGAGGCAGACGTCTGTCAGGGGCTTGGATTTCGTGTG CCGCTGCCACCCGCCCACCCGCCTTGTGAGATGGAATTGTAATAAACCACGCCATGAGGACACCGCCGC CCGCCTCGGCGCTTCCTCCACCGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001127190.2
Summary	The protein encoded by this gene is involved in multiple pathways, including the regulation of Src family kinases. It plays an important role in T-cell activation through its association with the protein encoded by the protein tyrosine phosphatase, non-receptor type 22 (PTPN22) gene. This protein also phosphorylates C-terminal tyrosine residues on multiple substrates, including the protein encoded by the SRC proto-oncogene, non-receptor tyrosine kinase gene. Phosphorylation suppresses the kinase activity of the Src family tyrosine kinases. An intronic polymorphism (rs34933034) in this gene has been found to affect B-cell activation and is associated with systemic lupus erythematosus (SLE). Alternative splicing results in multiple transcript variants. [provided by RefSeq, Aug 2017]
Locus ID	1445
MW	26.4

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