MTA2 (NM_004739) Human 3' UTR Clone

Specifications

Product Data
Product Name	MTA2 (NM_004739) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	MTA1L1; PID
ACCN	NM_004739
Insert Size	691 bp
Sequence Data	Insert Sequence (showhide) >SC208733 3’UTR clone of NM_004739 The sequence shown below is from the reference sequence of NM_004739. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACCAATGAGCCTATTGTCCTGGAGGACTGAGCACCTGTGGGGAAGGGAGGTGGGCTGAGAGGTAGAGGG TGGATGCCCAGGGCACCCAAACCTCCCTTCCCTTTCGTGTCGAAGGGAGTGAGGAGTGAATTAAGGAAG AGAGCAAGTGAGTGTGTGTCCCTGGAGGGGTTGGGCGCCCTCTGGTGTTACCACCTCGAGACTTGTCTC ATGCCTCCATGCTTGCCGATGGAGGACAGACTGCAGGAACTTGGCCCATGTGGGAACCTAGCCTGTTTT GGGGGGTAGGACCCACAGATGTCTTGGACAGTTTTGGGGGGAGGGTTTTTTAATTTTTTAAAAATTTTG CCTCCCTTTGTGAAAGGGGATGGGGAGGGGAAGAGTAAACAGATAACAGGTGGTGGTACCTGGTTGGGG GAGGGGGGCGTGCACTGCCATGTCTTTTTTTTTTTTTTTTTTTTTTTTTTTCCTAATTGGGGGTTTCTC TTTCTGTCCGGTGTCCGGACTTTCCTAATTGGAGTTTGAGGCCCCTAAGCTGGCATCAACCCCAGGCCA CGCTCGCTCTTTCCTTCCCTCCCCTCCCCCTCTGCCTTTTGTACGCCAGTTCTCAGAAATAAAGATCTT TTGTCCGTTTTTTTAACCTCGGATTCTGTAATTGGTTCTTATAGTAACAAATAAAAAGCTGTTTTCTTCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004739.4
Synonyms	MTA1L1; PID
Summary	This gene encodes a protein that has been identified as a component of NuRD, a nucleosome remodeling deacetylase complex identified in the nucleus of human cells. It shows a very broad expression pattern and is strongly expressed in many tissues. It may represent one member of a small gene family that encode different but related proteins involved either directly or indirectly in transcriptional regulation. Their indirect effects on transcriptional regulation may include chromatin remodeling. It is closely related to another member of this family, a protein that has been correlated with the metastatic potential of certain carcinomas. These two proteins are so closely related that they share the same types of domains. These domains include two DNA binding domains, a dimerization domain, and a domain commonly found in proteins that methylate DNA. One of the proteins known to be a target protein for this gene product is p53. Deacetylation of p53 is correlated with a loss of growth inhibition in transformed cells supporting a connection between these gene family members and metastasis. [provided by RefSeq, May 2011]
Locus ID	9219
MW	25.1

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