CD22 (NM_001771) Human 3' UTR Clone

Specifications

Product Data
Product Name	CD22 (NM_001771) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	SIGLEC-2; SIGLEC2
ACCN	NM_001771
Insert Size	694 bp
Sequence Data	Insert Sequence (showhide) >SC208730 3’UTR clone of NM_001771 The sequence shown below is from the reference sequence of NM_001771. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AATGTGGACTATGTGATCCTCAAACATTGACACTGGATGGGCTGCAGCAGAGGCACTGGGGGCAGCGGG GGCCAGGGAAGTCCCCGAGTTTCCCCAGACACCGCCACATGGCTTCCTCCTGCGCGCATGTGCGCACAC ACACACACACACGCACACACACACACACACACTCACTGCGGAGAACCTTGTGCCTGGCTCAGAGCCAGT CTTTTTGGTGAGGGTAACCCCAAACCTCCAAAACTCCTGCCCCTGTTCTCTTCCACTCTCCTTGCTACC CAGAAATCCATCTAAATACCTGCCCTGACATGCACACCTCCCCCTGCCCCCACCACGGCCACTGGCCAT CTCCACCCCCAGCTGCTTGTGTCCCTCCTGGGATCTGCTCGTCATCATTTTTCCTTCCCTTCTCCATCT CTCTGGCCCTCTACCCCTGATCTGACATCCCCACTCACGAATATTATGCCCAGTTTCTGCCTCTGAGGG AAAGCCCAGAAAAGGACAGAAACGAAGTAGAAAGGGGCCCAGTCCTGGCCTGGCTTCTCCTTTGGAAGT GAGGCATTGCACGGGGAGACGTACGTATCAGCGGCCCCTTGACTCTGGGGACTCCGGGTTTGAGATGGA CACACTGGTGTGGATTAACCTGCCAGGGAGACAGAGCTCACAATAAAAATGGCTCAGATGCCACTTCAA AGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001771.4
Synonyms	SIGLEC-2; SIGLEC2
Summary	Mediates B-cell B-cell interactions. May be involved in the localization of B-cells in lymphoid tissues. Binds sialylated glycoproteins; one of which is CD45. Preferentially binds to alpha-2,6-linked sialic acid. The sialic acid recognition site can be masked by cis interactions with sialic acids on the same cell surface. Upon ligand induced tyrosine phosphorylation in the immune response seems to be involved in regulation of B-cell antigen receptor signaling. Plays a role in positive regulation through interaction with Src family tyrosine kinases and may also act as an inhibitory receptor by recruiting cytoplasmic phosphatases via their SH2 domains that block signal transduction through dephosphorylation of signaling molecules.[UniProtKB/Swiss-Prot Function]
Locus ID	933
MW	24.9

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