CYP7B1 (NM_004820) Human 3' UTR Clone

Specifications

Product Data
Product Name	CYP7B1 (NM_004820) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	CBAS3; CP7B; SPG5A
ACCN	NM_004820
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC208711 3’UTR clone of NM_004820 The sequence shown below is from the reference sequence of NM_004820. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GTTTTATTTAGATACAAAGTGAAATCTTAGAGAAGCTAAAAGGAAAGAAAATAAATCTATCAAAATTAC CCTAAACATCCTAAGCTCATCTATTTCTTTTTAATTTCTGCAAATGTAATTGATTTATTTGTTTAAAAA GCGCTAATTTCTATTTGATCTGATATCAGTCCAGTTTGTCCTTAGTCACAAAGCCCATCATAATATAAA ACAGGATGGTGGCAGGAAAATGGACATCAAAATCAACTTAAGGGTAGGCTCAAAACAGGGTTGTTGTTG TTTTTTTAGTTTCTCCTTGTTGTGATTTTCACCTGTTATAATAAATGTACCTTCACACCAATAGATTGG GCACTGTGGAATTTAAATCACTCAAATTGTTCTCTAATATGTAAAATTACACTTTGAACTACTAGAAAA TTGTGCTGGAAATGGACACAGTCTAACAAATTCCAAATTCTCACAGAAGAAGGAAATTGAATTTCCATG AGTTACACTGGATGAAAATGTTCCCTTCAAGTATAATATTAATAATACCTATATTTCCAGGGTATGTGT GCATTAAATGAGTTTCACAGTAGATTGAATGCTTCAACTTCACTTCAATATTTAATCATGCATAAATGT TCCTTATTACTTTGTATACTATGGCTCAATAGAACAAAATTTCTGGTTACATAAGACCTTTCATGTTCA AGTTAGATACTGATAAGATTTAATGTATAAGAAAACACAGAACCTATTATATATTCAGAAATTGCCCTA GACATTAGTATTAGGTTTATTATGGGAGCAAATGTTGAAATAATTACAGCATTGATTATATCATTTGGC TTTAGTATAAACTATACAGGTTATGCAAATATTGCAATTAACCCTTTCCTAAATGCTTTCATATATATA AACTGAGAAGCTAGATATAGTATTTGGTTTTGATGTCTCACCTTTTGGATTTGGAGTTCATGTGTTCTA TTTTGAATTACAACATCATGTAATGCAGTGTAATTTCATATGACACATGCAGCATTGTGTCAATAATTC AAAGATTTTTTTTCAATTGAGAGAGTATCTGGCTGTGTTGCCCAGGCTGGTCTCAAATCCTGACCTCAA GTGATCCTCCCGCTTTGGTCCCTTGGGAACCTGGACTACAGGCATGTACCACCAAGCCCAGTGATTCAA AGATTCTAATATCAGAGTACCACATGATTGGCATCTGATATAAATGATGATGCAATATATAAGCAGGCA AGGCAGGTAATAAAGTCCAGTTAATTCATGCTTCGTTAATTGGAACTTCTAATATTTCAGAAATCTGCT ACTGTTTTGAGAAAAGGAAACTGACTTTAAAAATAACATTACAAAATATTTACATTCTTAGTAAGTAAA TAAGACAGTCTAGCATTTATTTTATCCTTCCTGAAGTACATGTTCTGAATGTTCCTTCAGTGAAGGTCT GCTGGTGCAAATTCTATTTTTGCTTGATTTAGGGTGTCTTTATTTTTACTCTCCTTCTTGAAAGATGGT TTTGCTGGATGCACAAATCTAGATTGACAGTTATTTCCTCACAGCACTTTGAAGATATTGCCCGTTCTT AAGGTATCCATTGTTGTTATTGGGCGGATAGCCGTTAGTGAGTTTAATTACTCAATAGGTAGTCTGTCT CTTCTCTCTGACTACTTTAACGTGTCCTCTTTGTCTTTGATGTTCTTAGTTTCTTTCTGTTTCTCATGC TTGCATGTCCTGCTGCTTCTTGAATCTGAGCACAGGTGTCTCCCATCAAGTATGGAATCTTCTCAGCCA TTCTCTCTGTGAATATTACTGTTCTCACACTCTACATTAGATCCTCTCACTCTACATACATCCTTTGAT CTTTTCTCACCACACTTTGTATCTCTAACTTACACTCCATGTAATTTCTTTAGATGTCTCTTCCAGTTT CTTCTTTGAACAGTATATCTAATCTCTCCAACTCATCCACTGAGTTTGTTTTTTCCTTCTTTTTGTTT ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_004820.5
Synonyms	CBAS3; CP7B; SPG5A
Summary	This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This endoplasmic reticulum membrane protein catalyzes the first reaction in the cholesterol catabolic pathway of extrahepatic tissues, which converts cholesterol to bile acids. This enzyme likely plays a minor role in total bile acid synthesis, but may also be involved in the development of atherosclerosis, neurosteroid metabolism and sex hormone synthesis. Mutations in this gene have been associated with hereditary spastic paraplegia (SPG5 or HSP), an autosomal recessive disorder. [provided by RefSeq, Apr 2016]
Locus ID	9420
MW	76.6

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