PAR4 (PAWR) (NM_002583) Human 3' UTR Clone

Specifications

Product Data
Product Name	PAR4 (PAWR) (NM_002583) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	Par-4; PAR4
ACCN	NM_002583
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC208575 3’UTR clone of NM_002583 The sequence shown below is from the reference sequence of NM_002583. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TTGAAAGTTGTGGGTCAGCTGACCAGGTAGAGGATTCAAGACTCAATGTGGAAAAAATATTTTAAACTA CTGATTGAATGTTAATGGTCAATGCTAGCACAATATTCCTATGCTGCAATACATTAAAATAACTAAGCA AGTATATTTATTTCTAGCAAACAGATGTTTGTTTTCAAAATACTTCTTTTTCATTATTGGTTTTAAAAA AGCATTATCCTTTTATCTCACAAATAAGTAATATCTTTCAGTTATTAAATGATAGATAATGCCTTTTTG GTTTTGTGTGGTATTCAACTAATACATGGTTTAAAGTCACAGCCGTTTGAATATATTTTATCTTGGTAG TACATTTTCTCCCTTAGGAATATACATAGTCTTTGTTTACATGAGTTCAAATACTTTTGGGATGTTACC TTCACATGTCCTATTACTGATGTGTGCAACCTTTTATGTGTTGATGACTCACTCATAAAGGTTTTTGTC TACTGTCATTTGTTCTTTCCACTTATTCTAAGCATTTAGAGTAATAGAGTCATACTTTTTTATAACAGC AACCTTTTAAAAGGAAAGCTCTTATAAAGTCACTGTCATGTTTTAGTTGACTAAATATAAATTTAAGAG AATACTTGAATTGTGCTATAGTAAATAAAAATTTACTATTTTGTGTTTGAATATTGAAAAATTGAATCA CTTTAACTCCTGAAAAACATACAATTGTAATTTCAATGTAAAATTTCTTATGTAGGTACTACCTTTTTT TATCGTTCCAAGGTTTGCTAGTGAACACAGGATATTTTAAAAGTTTTTTATTCTTCGGGCCTGGAAAGT GTACAAAGTCAGTGTAGGAGAAAAAAATCCATATTTTTATATTAGCATGCACACTAAAAACCAAAATAT TATTCATACTTAAAACATTCATACAAAACAATATGTAAGCAGAAATAGTACTAAAATACTTTGCCTAAT TTCTAAGTTGAAGAATAACACTGGGACACAGTTTTTTCATATGAGAGAATATTCCGCTATTTCAAATTT AAGGGATTTTCTTCCTAACATTGAAATTTTAAAAACAGAGTTACTTCTAAATAATTATACAGATTTTTT CTTCTATTAAATATTATTATTTAGAATTGTTTTTGTATTACATATTCATGTTAAGAACCCCGTCTTCCC TTAAAATACATTAAAATTATGACATTTTTGCTTTGTGATTGAATTTCAAATAGCAGTATGGTATCCTTT TATCTAGTTAATATATGAAAGTGGCTTGAATATAGTCAAATCCATTTTAGGTACTCTACTGACTTTTTC CTTCACTTGCCAAGCCCTTTTATTGTTCACTGTTAGAAAAATAGAGAAGGTGAGACAGCTGGGGGAAAA TGTGGAGTAAATGATAATCAAATGTTGAATTCTAAAAGTCTCTACATTTACCTAGGTTGGCTTTCTCCC CCAGTTCAGAAGTTTCCAGCTTGGCCAATCATCAGAATCACTTGAGGAACTTAGAAAGAACTCCCTGGC TGTAGCTCCTATGTAGGTTTAGGTTGAGACTCTGGATTCCACAATTTTTAAAGGTTACCATCTGAGGTT TCTGATCATAGTCTACTTTTGAAGCAGCTGCTGCTGTTTCTTTATTCCATTGAACACCCTGGAATTGAC ATAATTTTATCTATCAGCATTTCTCCCCTTTTAGTTTATTTAATAATTAACCCGGTCTCCAGGGCAGTT TTCATATGACCATGTGTATATTCACTGCTCACGAAAAAGTTTAATGTTAGATTACCAAATTTAATATAG TTACAGAATTACTGCATAAGGGCTTCCCTTCTTGGAGACTCTTACCCAGCATGGGAACAGTGATCTGCC CACATGACAGGGTGGTATGCCAGGCATAGTTAACTGCTTTTGGTTGTGAGGTACTCATCTTCCTTTAGT TACCCTTAGTTATGTGGCACACATGTCCTTATTGCCTAGTTCGTCATCCACACTTTGGATCTTGTGAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002583.4
Synonyms	Par-4; PAR4
Summary	This gene encodes a tumor suppressor protein that selectively induces apoptosis in cancer cells through intracellular and extracellular mechanisms. The intracellular mechanism involves the inhibition of pro-survival pathways and the activation of Fas-mediated apoptosis, while the extracellular mechanism involves the binding of a secreted form of this protein to glucose regulated protein 78 (GRP78) on the cell surface, which leads to activation of the extrinsic apoptotic pathway. This gene is located on the unstable human chromosomal 12q21 region and is often deleted or mutated different tumors. The encoded protein also plays an important role in the progression of age-related diseases. [provided by RefSeq, Aug 2017]
Locus ID	5074
MW	78.2

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