PTPN13 (NM_080685) Human 3' UTR Clone

Specifications

Product Data
Product Name	PTPN13 (NM_080685) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	FAP-1; hPTP1E; PNP1; PTP-BAS; PTP-BL; PTP1E; PTPL1; PTPLE
ACCN	NM_080685
Insert Size	640 bp
Sequence Data	Insert Sequence (showhide) >SC208333 3’UTR clone of NM_080685 The sequence shown below is from the reference sequence of NM_080685. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CAAAAACAGCAGCCTCAGCTTCTGAAGTGACATGAAAAGAGCCTCTGGATGCATTTCCATTTCTCTCCT TAACCTCCAGCAGACTCCTGCTCTCTATCCAAAATAAAGATCACAGAGCAGCAAGTTCATACAACATGC ATGTTCTCCTCTATCTTAGAGGGGTATTCTTCTTGAAAATAAAAAATATTGAAATGCTGTATTTTTACA GCTACTTTAACCTATGATAATTATTTACAAAATTTTAACACTAACCAAACAATGCAGATCTTAGGGATG ATTAAAGGCAGCATTTGATGATAGCAGACATTGTTACAAGGACATGGTGAGTCTATTTTTAATGCACCA ATCTTGTTTATAGCAAAAATGTTTTCCAATATTTTAATAAAGTAGTTATTTTATAGGGGATACTTGAAA CCAGTATTTAAGCTTTAAATGACAGTAATATTGGCATAGAAAAAAGTAGCAAATGTTTACTGTATCAAT TTCTAATGTTTACTATATAGAATTTCCTGTAATATATTTATATACTTTTTCATGAAAATGGAGTTATCA GTTATCTGTTTGTTACTGCATCATCTGTTTGTAATCATTATCTCACTTTGTAAATAAAAACACACCTTA AAACATGAACAAGCCAAAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_080685.3
Synonyms	FAP-1; hPTP1E; PNP1; PTP-BAS; PTP-BL; PTP1E; PTPL1; PTPLE
Summary	The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP is a large intracellular protein. It has a catalytic PTP domain at its C-terminus and two major structural domains: a region with five PDZ domains and a FERM domain that binds to plasma membrane and cytoskeletal elements. This PTP was found to interact with, and dephosphorylate, Fas receptor and IkappaBalpha through the PDZ domains. This suggests it has a role in Fas mediated programmed cell death. This PTP was also shown to interact with GTPase-activating protein, and thus may function as a regulator of Rho signaling pathways. Four alternatively spliced transcript variants, which encode distinct proteins, have been reported. [provided by RefSeq, Oct 2008]
Locus ID	5783
MW	24.8

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