Glutathione Reductase (GSR) (NM_000637) Human 3' UTR Clone

Specifications

Product Data
Product Name	Glutathione Reductase (GSR) (NM_000637) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	GR; GSRD; HEL-75; HEL-S-122m
ACCN	NM_000637
Insert Size	1484 bp
Sequence Data	Insert Sequence (showhide) >SC207968 3’UTR clone of NM_000637 The sequence shown below is from the reference sequence of NM_000637. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TCTTCAGAAGAGCTGGTCACACTTCGTTGAGAACCAGGAGACACGTGTGGCGGGCAGTGGGACCCATAG ATCTTCTGAAATGAAACAAATAATCACATTGACTTACTGTTTGAGTTTTATGTATTTCTTTATTTTAAT CAGGATCTTCTGATAGTGGAAATTTTTAGTACATAATAGAACTTATTTATGGAGTTAGAAATTTGTAGT GTTATCCAGGATTGATTTTCATTTGATCACATCTCACAGTAATTAATATTTTCAAGTTTTTTTTTTATT AACAGCTCTGTGCTAGTTTTTTTTTTCTGTTTTAGCCTCATCCCAAATATAAAGCTTTGTGAAGTACAA TTAACTTAATGTACTTGAATGAATAGAACTTGCTACTTTTTTTTTTTTTTTTTTTGAGACAGAGTTTTG CTCTCATTGCCCAGGCTGGAGTGCGGTGGTGCTATTTCAGCTCACCACAACCTCTGCCTCCTGGGTTCA AGTGATTCTCCTGCCTTAGCCTCCCGAATAGCTGGAATTACAGGCACGCACCACCATGCCTGACTAATT TTGTATTTTTAGTAGACATGGGGTTTCTCCATGTTGGTCAGGCTGGTCTCAAACTCCCACCTTCAGGTG ATCCGCCCACCTCGGCCTCCTGAGGTGCTGAGATTACAGGCGTGAGCCACTGTGCCAGCTTGCTAATTT TCACAGAAGTTGATGGCAATTCTTCACATGTAAACAGTGCCAGTGCACAGAACCTTTATATATTTTTTG AAGCCAGTACTGTGCTCTGCATATAACAAAGCTGCTTCAAGGATGAGACCTTTTTCTAAAAGCATGTAA TGTGAGAAGCCGGCCTGCCTTATTTTCTTTTTTCTTTTTTAATGATTAAAAATAGTTTGTGGCAAGGCA CGGTGGCTCAGGCCTGTAATTCTAGCACTTTGGGAGGCCGAGGCAGGAGGATTACTTGAGCCTACAAGT TTGAGGCCAGCATGCACAGCATAGCAAGACTGCATCTCTACAGAGAGTAAAAAAAATTACCCGAGTGTG GTGATGTGCATCTGTAATCTCAGCTACTTGGGAGGCTGAGGTGAGAGGATCACTTGAGCTTGGGTGAGG TGAGGCTGCAGTGAGTCCTGATCATGCTGCTGCACTCAATCTTGGACAACAGAGCAAGACCCTGTCTCA AAAAAAAAAAAAAAAAATATATATATATATATATATTATTTTTATGAGGTGAAGTGCATCAAACTTGGG AAAGATTTGAGGAGGCTGGGAACCTCCTGGAAAACCACTCCTTGAAGAAAGATATGAGAGACATTTAGA AGTGATTCCTGCTTTCAGAAGGAGGTGGATTCAAATACATCAAAAGTCCCTTCCTCTGCTAAGTGTTTA TAGTTCAATGAATAATTTCAATATTTGTATGTGTTCTTGTCATTTTATTTTTTTCTGAAAAACTTCCAA AAATTTGAAAATAAAATTACAGCCTTTTCTTCTTA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000637.5
Synonyms	GR; GSRD; HEL-75; HEL-S-122m
Summary	This gene encodes a member of the class-I pyridine nucleotide-disulfide oxidoreductase family. This enzyme is a homodimeric flavoprotein. It is a central enzyme of cellular antioxidant defense, and reduces oxidized glutathione disulfide (GSSG) to the sulfhydryl form GSH, which is an important cellular antioxidant. Rare mutations in this gene result in hereditary glutathione reductase deficiency. Multiple alternatively spliced transcript variants encoding different isoforms have been found. [provided by RefSeq, Aug 2010]
Locus ID	2936
MW	56.8

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