BAI1 (ADGRB1) (NM_001702) Human 3' UTR Clone

Specifications

Product Data
Product Name	BAI1 (ADGRB1) (NM_001702) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	BAI1; GDAIF
ACCN	NM_001702
Insert Size	620 bp
Sequence Data	Insert Sequence (showhide) >SC207907 3’UTR clone of NM_001702 The sequence shown below is from the reference sequence of NM_001702. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GACATCATCGACCTCCAGACCGAGGTCTGAGCGGGTGGGCGGCGGCCACGCACTGGGCCACGGAGGAGG GATGCTGCTCCGCCCGCTCCTGCCGCAGACGGGCACAGACACGCTCGCGGGCAGCGGGCCAGGCCCGCA CCCCGGCCTCAGGGCGCTCAGACGGCGGCCAGGCACAGGGCCCGCAGTGCTGGGACCAGAGCCAGATGC AGGACAGGAGGCGGCCCGGCCAGCGGGCACAGGGCACCAGAGGCCGAAGGTGCCTCAGACTCCGCCCTC CTCGGGCCGAGGCCCAGCGGGCAGATGGGCGGACGGCTGTGGACCGTGGACAGGCCCAGCGCGGCCAGC GTCCCAGGGTACCCGCCTGAGCTCCTGCTGCGGAGGAGCTGCCTGCTTGGCCCGGCCGGCCTGGCACCG TTTTTTAAACACCCCCATCCCTCGGGAAGCAGCCAGCTCCCCACACCTTCCAGGGCCCTAGGCCCCTCC TAGACCCAGGTGGAGGGCACAGCCCTCCGACCCTCATGGCCCCCAGGGGCAGGACTGAGTCCCCTCCAG GAAGAAGCAGGGGGGAATCTATTTTTTCTCTCCTTTTCTTTTCTTCAATAAAAAGAATTAAAAACCCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001702.3
Synonyms	BAI1; GDAIF
Summary	Angiogenesis is controlled by a local balance between stimulators and inhibitors of new vessel growth and is suppressed under normal physiologic conditions. Angiogenesis has been shown to be essential for growth and metastasis of solid tumors. In order to obtain blood supply for their growth, tumor cells are potently angiogenic and attract new vessels as results of increased secretion of inducers and decreased production of endogenous negative regulators. BAI1 contains at least one 'functional' p53-binding site within an intron, and its expression has been shown to be induced by wildtype p53. There are two other brain-specific angiogenesis inhibitor genes, designated BAI2 and BAI3 which along with BAI1 have similar tissue specificities and structures, however only BAI1 is transcriptionally regulated by p53. BAI1 is postulated to be a member of the secretin receptor family, an inhibitor of angiogenesis and a growth suppressor of glioblastomas [provided by RefSeq, Jul 2008]
Locus ID	575
MW	21.6

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