beta 2 Adrenergic Receptor (ADRB2) (NM_000024) Human 3' UTR Clone

Specifications

Product Data
Product Name	beta 2 Adrenergic Receptor (ADRB2) (NM_000024) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ADRB2R; ADRBR; B2AR; BAR; BETA2AR
ACCN	NM_000024
Insert Size	580 bp
Sequence Data	Insert Sequence (showhide) >SC207676 3’UTR clone of NM_000024 The sequence shown below is from the reference sequence of NM_000024. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AATTGTAGTACAAATGACTCACTGCTGTAAAGCAGTTTTTCTACTTTTAAAGACCCCCCCCCCCAACAG AACACTAAACAGACTATTTAACTTGAGGGTAATAAACTTAGAATAAAATTGTAAAATTGTATAGAGATA TGCAGAAGGAAGGGCATCCTTCTGCCTTTTTTATTTTTTTAAGCTGTAAAAAGAGAGAAAACTTATTTG AGTGATTATTTGTTATTTGTACAGTTCAGTTCCTCTTTGCATGGAATTTGTAAGTTTATGTCTAAAGAG CTTTAGTCCTAGAGGACCTGAGTCTGCTATATTTTCATGACTTTTCCATGTATCTACCTCACTATTCAA GTATTAGGGGTAATATATTGCTGCTGGTAATTTGTATCTGAAGGAGATTTTCCTTCCTACACCCTTGGA CTTGAGGATTTTGAGTATCTCGGACCTTTCAGCTGTGAACATGGACTCTTCCCCCACTCCTCTTATTTG CTCACACGGGGTATTTTAGGCAGGGATTTGAGGAGCAGCTTCAGTTGTTTTCCCGAGCAAAGTCTAAAG TTTACAGTAAATAAATTGTTTGACCATG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000024.6
Synonyms	ADRB2R; ADRBR; B2AR; BAR; BETA2AR
Summary	This gene encodes beta-2-adrenergic receptor which is a member of the G protein-coupled receptor superfamily. This receptor is directly associated with one of its ultimate effectors, the class C L-type calcium channel Ca(V)1.2. This receptor-channel complex also contains a G protein, an adenylyl cyclase, cAMP-dependent kinase, and the counterbalancing phosphatase, PP2A. The assembly of the signaling complex provides a mechanism that ensures specific and rapid signaling by this G protein-coupled receptor. This receptor is also a transcription regulator of the alpha-synuclein gene, and together, both genes are believed to be associated with risk of Parkinson's Disease. This gene is intronless. Different polymorphic forms, point mutations, and/or downregulation of this gene are associated with nocturnal asthma, obesity, type 2 diabetes and cardiovascular disease. [provided by RefSeq, Oct 2019]
Locus ID	154
MW	22.3

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