Syntrophin alpha 1 (SNTA1) (NM_003098) Human 3' UTR Clone

Specifications

Product Data
Product Name	Syntrophin alpha 1 (SNTA1) (NM_003098) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	dJ1187J4.5; LQT12; SNT1; TACIP1
ACCN	NM_003098
Insert Size	580 bp
Sequence Data	Insert Sequence (showhide) >SC207440 3’UTR clone of NM_003098 The sequence shown below is from the reference sequence of NM_003098. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAAGTCACCCGCCTCGGGCTGTTGGCCTAGAAGTCGCCGGATGCACTAGCCCTGAAGAGGGGTGTCCAT GACATGGCCTGAGCTGGGCCTCCACCGACTGCCTGCTCACCCCTGGGCTGAGGGAAGGGAGAGGAGAGG AACAAGGGCCTCCGAAACCCCAACCCTGAGGGAGACTGGATTGGTCTTGGGGCCCAGGACCCAGACGCA GGACAGAGTGGACTCTGCCTGTGATGGGGTGGCCTTCCTGCTGCCCCCCTCCACCAGTGCCTTTTGCAG AGAGATATTTTGTGTACACAGAAGCCATTCCGAGTCTGGGACCTGCCCCTGTGCGGATCCTGACCCCAG CCAACAGCTGAGCTGCCGGGCCTCCTCGAGGCCCCTAAGCCACCCCCAGAGGTCCCATCTGAAGCTGGA GTACCCTGGGGTCAGCAGCAAGAGAAAGAAGAGGAGATTTTCTGTTTGTTTTTCCCCTCAGCCCTGCCA CCGTGGGGAGTCTGGTTTTTCTCTTCATCCTGTCTCTCTCCTCCTTACTCTTGGATAAATAAACAGCCT GTGAGCACACAGGCAGCCCGGCCCAGTG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003098.3
Synonyms	dJ1187J4.5; LQT12; SNT1; TACIP1
Summary	Syntrophins are cytoplasmic peripheral membrane scaffold proteins that are components of the dystrophin-associated protein complex. This gene is a member of the syntrophin gene family and encodes the most common syntrophin isoform found in cardiac tissues. The N-terminal PDZ domain of this syntrophin protein interacts with the C-terminus of the pore-forming alpha subunit (SCN5A) of the cardiac sodium channel Nav1.5. This protein also associates cardiac sodium channels with the nitric oxide synthase-PMCA4b (plasma membrane Ca-ATPase subtype 4b) complex in cardiomyocytes. This gene is a susceptibility locus for Long-QT syndrome (LQT) - an inherited disorder associated with sudden cardiac death from arrhythmia - and sudden infant death syndrome (SIDS). This protein also associates with dystrophin and dystrophin-related proteins at the neuromuscular junction and alters intracellular calcium ion levels in muscle tissue. [provided by RefSeq, Jan 2013]
Locus ID	6640
MW	20.8

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