KCNN3 (NM_002249) Human 3' UTR Clone

Specifications

Product Data
Product Name	KCNN3 (NM_002249) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	hSK3; KCa2.3; SK3; SKCA3; ZLS3
ACCN	NM_002249
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC207368 3’UTR clone of NM_002249 The sequence shown below is from the reference sequence of NM_002249. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC ACCCCGTACACAAGTTCAAGCAGTTGCTAAATAAATCTCCCCACTCCAGAAGCATTACCCATAGGTCTT AAGATGCAAATCAACTCTCTCCTGGTCGCTTTGCCATCAAGAAACATTCAGACCAGGGAACGGAAAGAA GAGAGACCGAGCTAATTAACTAACTCATGTTCATTCAGCGTGCTTGGTCCGACATGCCTTGAAACCAGA AATCTAATCTCTGTTTAGGTGCCTCTACTTGGGAGCGGGAAGAGGAGATGACAGGAAGCGACGCCTCTG GCAGGGCCCTTGCTGCAGAGTTGGTGGAGAACAGAAATCCACGCTCAATCTCAGGTCTTCACGCGGGGG GTGGGGGTCAGATGCACTGAAGTAGCCAACAGCGAAGCCAGTCCAGAAGAGGGGTCCGCTGGGAGGGAG GGTTGTGTCAGGCTTGGGGGATGGGCTCTTCGCCATGGGGGTCTTTGAACACACCTCTCTCCTTTCCTT TTGTCTACGGAAGCCTCTGGGTGACAAAAGTAAAAGAGAGCTGCCCACAACTTGCCAAAACAGATATAC TCGAATCAGACTGAAAAAAAAAAAAAAAGACACAGACAAATAAAAAGCCAGATTTTCCACTCGATATTA ATACCCACATAAACCTGTGTGTTTGCAAACGTGTACATGTACACACATACACATCCCACGTTCGCTTCA GGTCCTTTCTTATTTGAGCTTAATCCAAATAAAAAGGGACTTGACACCTTACCCTGCATACAATAGGCA CCCCTTACATGTGTTTTGAGTTGGTCTGAATCTGAACATGGGGTGCTTTCAGTTCAGGTAGTTAGCTAG TTCTGGCCACATTCTGAGTTTCACTGAAGATGTGGATCCCTTCAGACATAATGCACATTGCTTTGTCCT GGATATGCACCTTGCTTGATTTGAAATGGATGCCAAGCCAAAATTGTTGGCATTCAGGAGGGATAAGCA GGCTTCTAAAAATAACAGCATCTGCAGAGTTTTCTTCTTCCATCCAAACAAGTTGTGTTTCGATGGTCC ACATGACCAGGTGTATGTCTGTAAGTGTGGAGGGAGAGGACAAGAAATTGTGCATGTGTGTGCAGACAT GCACAAACAGGAGCAATCCAATAACACCTTAGTGAATAGAAATATGGTTGGGGATTTGCTGAGCTGTAT TTATCCAGCAACAGGTTTCCAGCCCCAGATGTTAGTAGTGCAAAAGGGCCAAGTGCCTCAATTGTGAGC CTCTGAGCTAGGAGGAGAAGTGATGAAGAGTGGCCTATGTGGTCCCTTCTACCTGACCTTAAGTCATCT CAAAATGAAATATTGTGAGAATGAAGGGAACCCTTAGGGAACCTTGTGGGTAAGGTAAGTGGACATGGA TTTGTCAGTAGCCTGTTCCTACTGTGCCATGTTAATCTTGGTGCGAAAAACTATTCCAATACATCTCAA ACTCCAAGAGACTTCAGAAACATCAAGATTTAGTGTAATGAGCGGCGCAGAAAAATGTTTTCATTGCTC CATAATCTGACCACACGTAACATTTGTGACGTGAAAACCATGACTTTCTCATTCTGAGGTCTTTGGTTT CTGCCTGTGGGAAATTGAATGGCACTGTATGGACTATTTCATCTGTTGATGGTAAAACAAAAGGGTGAT TTTTTTGCTTGTGGTTGTCATCTTGGGTTTACCTTTGTAAGAAGACATCATCACCATTCTGAAGGCAGT GGCTTGGCATGGAGATTTTTATTCTGTAGCACTGGGCCTGTTCTTCTAAGGACAGCACAAGGTAGACAA TTGTAGAGCCAAGGCCACTTTTTCAGGAAGATCTAGTCTCTTGCTAACCCTCTTCTTTCTCTCTTGCTA TTGCTGCTGCTCTTTTGATGGTTTATAGTCTTAATGGCCTGCCTTGATAATTCCTTTGAACACTTTCAT TAGTTGTTTTGCATACCAGAGATGCCGCACCTGCTGTTGGCTTATTTTTTTACTTGTTCTATTAACTG ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002249.6
Synonyms	hSK3; KCa2.3; SK3; SKCA3; ZLS3
Summary	Action potentials in vertebrate neurons are followed by an afterhyperpolarization (AHP) that may persist for several seconds and may have profound consequences for the firing pattern of the neuron. Each component of the AHP is kinetically distinct and is mediated by different calcium-activated potassium channels. This gene belongs to the KCNN family of potassium channels. It encodes an integral membrane protein that forms a voltage-independent calcium-activated channel, which is thought to regulate neuronal excitability by contributing to the slow component of synaptic AHP. This gene contains two CAG repeat regions in the coding sequence. It was thought that expansion of one or both of these repeats could lead to an increased susceptibility to schizophrenia or bipolar disorder, but studies indicate that this is probably not the case. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2011]
Locus ID	3782
MW	74.8

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