Kallikrein 6 (KLK6) (NM_002774) Human 3' UTR Clone

Specifications

Product Data
Product Name	Kallikrein 6 (KLK6) (NM_002774) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	Bssp; hK6; Klk7; PRSS9; PRSS18; SP59
ACCN	NM_002774
Insert Size	563 bp
Sequence Data	Insert Sequence (showhide) >SC207348 3’UTR clone of NM_002774 The sequence shown below is from the reference sequence of NM_002774. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC TGGATCCAAAAAACCATTCAGGCCAAGTGACCCTGACATGTGACATCTACCTCCCGACCTACCACCCCA CTGGCTGGTTCCAGAACGTCTCTCACCTAGACCTTGCCTCCCCTCCTCTCCTGCCCAGCTCTGACCCTG ATGCTTAATAAACGCAGCGACGTGAGGGTCCTGATTCTCCCTGGTTTTACCCCAGCTCCATCCTTGCAT CACTGGGGAGGACGTGATGAGTGAGGACTTGGGTCCTCGGTCTTACCCCCACCACTAAGAGAATACAGG AAAATCCCTTCTAGGCATCTCCTCTCCCCAACCCTTCCACACGTTTGATTTCTTCCTGCAGAGGCCCAG CCACGTGTCTGGAATCCCAGCTCCGCTGCTTACTGTCGGTGTCCCCTTGGGATGTACCTTTCTTCACTG CAGATTTCTCACCTGTAAGATGAAGATAAGGATGATACAGTCTCCATAAGGCAGTGGCTGTTGGAAAGA TTTAAGGTTTCACACCTATGACATACATGGAATAGCACCTGGGCCACCATGCACTCAATAAAGAATGAA TTTTATTATGA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_002774.4
Synonyms	Bssp; hK6; Klk7; PRSS9; PRSS18; SP59
Summary	This gene encodes a member of the kallikrein subfamily of the peptidase S1 family of serine proteases. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. The encoded preproprotein is proteolytically processed to generate the mature protease. Expression of this protease is regulated by steroid hormones and may be elevated in multiple human cancers and in serum from psoriasis patients. The encoded protease may participate in the cleavage of amyloid precursor protein and alpha-synuclein, thus implicating this protease in Alzheimer's and Parkinson's disease, respectively. This gene is located in a gene cluster on chromosome 19. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed. [provided by RefSeq, Feb 2016]
Locus ID	5653
MW	21.2

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