AUH (NM_001698) Human 3' UTR Clone

Specifications

Product Data
Product Name	AUH (NM_001698) Human 3' UTR Clone
Vector	pMirTarget
ACCN	NM_001698
Insert Size	555 bp
Sequence Data	Insert Sequence (showhide) >SC207329 3’UTR clone of NM_001698 The sequence shown below is from the reference sequence of NM_001698. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC AAAAGGCCCCCTCGCTATAAAGGAGAATAAAAGGAACAGAAATTCTTAAGATGCCAATGTAATAAATGT ACTTCCTGGAAGTGTCTTTCGGATCCACTATATGCCTCAGCACATGGAACCTTAATGACCAAAGTGAAG AGCAGATTATTCATACGGTGTAATAAGCATCTGGAATGGACCCATCCGTGTACTTCATTCAAATGTGTA AATGTCATATTCATTCAGATTTATAAAGCTAGTAGTGTATAGTCAGAAACAGAATCAAAGTTAGATATA CATTTTTAAATATTTACTGCATATGAGGCTTTCTGTTAATTTTTTAATGTGAATAATTTATATATTGCA CATTCTAGGGAATAATATTGATTGTATGTCTACTGTGCTGCATTAAGAAAATAAAATTTCTATATACCA AAAATGTGAAGTTATACCAAATAAAGTTTCTAAGTGATTAATGCATACGAACAGCTACATATACATATA TCTAAACCTGAAAAATGAATTGATATTCTGAGTGAAAACTACCTAATATAAATAAAATTAGTGAAAAGA AAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_001698.3
Summary	This gene encodes bifunctional mitochondrial protein that has both RNA-binding and hydratase activities. The encoded protein is a methylglutaconyl-CoA hydratase that catalyzes the hydration of 3-methylglutaconyl-CoA to 3-hydroxy-3-methyl-glutaryl-CoA, a critical step in the leucine degradation pathway. This protein also binds AU-rich elements (AREs) found in the 3' UTRs of rapidly decaying mRNAs including c-fos, c-myc and granulocyte/ macrophage colony stimulating factor. ARE elements are involved in directing RNA to rapid degradation and deadenylation. This protein is localizes to the mitochondrial matrix and the inner mitochondrial membrane and may be involved in mitochondrial protein synthesis. Mutations in this gene are the cause of 3-methylglutaconic aciduria, type I. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
Locus ID	549
MW	22

*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.