alpha 2C Adrenergic Receptor (ADRA2C) (NM_000683) Human 3' UTR Clone

Specifications

Product Data
Product Name	alpha 2C Adrenergic Receptor (ADRA2C) (NM_000683) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	ADRA2L2; ADRA2RL2; ADRARL2; ALPHA2CAR
ACCN	NM_000683
Insert Size	561 bp
Sequence Data	Insert Sequence (showhide) >SC207122 3’UTR clone of NM_000683 The sequence shown below is from the reference sequence of NM_000683. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CGACGGAGGAGAAGGGGCTTCAGGCAGTGACTCGCACCCGTCTGGGAATCCTGGACAGCTCCGCGCTCG GGGCTGGGCAGAAGGGGCGGCCCGGACGGGGGAGCTTTCCCAGAGACCCGGGGATGGATTGGCCTCCAG GGCGCAGGGGAGGGTGCGGCAGGGCAGGAGCTTGGCAGAGAGATAGCCGGGCTCCAGGGAGTGGGGAGG AGAGAGGGGGAGACCCCTTTGCCTTCCCCCCTCAGCAAGGGGCTGCTTCTGGGGCTCCCTGCCTGGATC CAGCTCTGGGAGCCCTGCCGAGGTGTGGCTGTGAGGTCAGGGTTTTAGAGAGCAGTGGCAGAGGTAGCC CCCTAAATGGGCAAGCAAGGAGCCCCCCAAAGACACTACCACTCCCCATCCCCGTCTGACCAAGGGCTG ACTTCTCCAGGACCTAGTCGGGGGGTGGCTGCCAGGGGGCAAGGAGAAAGCACCGACAATCTTTGATTA CTGAAAGTATTTAAATGTTTGCCAAAAACAACAGCCAAAACAACCAAACTATTTTCTAAATAAACCTTT GTAATCTAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000683.4
Synonyms	ADRA2L2; ADRA2RL2; ADRARL2; ALPHA2CAR
Summary	Alpha-2-adrenergic receptors are members of the G protein-coupled receptor superfamily. They include 3 highly homologous subtypes: alpha2A, alpha2B, and alpha2C. These receptors have a critical role in regulating neurotransmitter release from sympathetic nerves and from adrenergic neurons in the central nervous system. The mouse studies revealed that both the alpha2A and alpha2C subtypes were required for normal presynaptic control of transmitter release from sympathetic nerves in the heart and from central noradrenergic neurons. The alpha2A subtype inhibited transmitter release at high stimulation frequencies, whereas the alpha2C subtype modulated neurotransmission at lower levels of nerve activity. This gene encodes the alpha2C subtype, which contains no introns in either its coding or untranslated sequences. [provided by RefSeq, Jul 2008]
Locus ID	152
MW	19.9

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