GSTA2 (NM_000846) Human 3' UTR Clone

Specifications

Product Data
Product Name	GSTA2 (NM_000846) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	GST2; GSTA2-2; GTA2; GTH2
ACCN	NM_000846
Insert Size	520 bp
Sequence Data	Insert Sequence (showhide) >SC206753 3’UTR clone of NM_000846 The sequence shown below is from the reference sequence of NM_000846. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GAAGAATCAAGGAAGATTTTCAGGTTTTAATAAACCAGCCATAGAGGTCAAGAACATGCAAGACCAGTA TTCTAAAGTTTTGCAACAATTAAGTGCTTTACCTAAGTGTTGATTGTGCCTGTTGTGAAGCTAATGAAC TCTTTCAAATTATATGCTAATTAAATAATACAACTCCTATTCACCCACTTAGTTAAAATTGATTTCTTC TCATTAGGATCTGATGTGAATTCAGTTTTCCAATCTCCTCCTAGCCAACAATTTTCTTGGAATTACAAA TTCAGTAAAAATGGAAACTATAAATTATGTGGTTTGTTTGACTTTTCCAAGAATTGCCCTGTAACATAC AATTTGTCATACAATCTATTAAAATGCCAATGTAAAAATGCACCTCTGACATTTTCAGGTATGCACAGG AGAAGAGTTACCATCCTGGATAATGGCATAAAGACATTTTCTTCTTTTCCTGAACAGTCATTTTATTTC TGATAAAAGCATTCTTTCTAATGCATTTGCAAAACAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_000846.5
Synonyms	GST2; GSTA2-2; GTA2; GTH2
Summary	Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding these enzymes are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of some drugs. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-tranferase belonging to the alpha class. The alpha class genes, located in a cluster mapped to chromosome 6, are the most abundantly expressed glutathione S-transferases in liver. In addition to metabolizing bilirubin and certain anti-cancer drugs in the liver, the alpha class of these enzymes exhibit glutathione peroxidase activity thereby protecting the cells from reactive oxygen species and the products of peroxidation. [provided by RefSeq, Jul 2008]
Locus ID	2939
MW	20.1

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