RMND5B (NM_022762) Human 3' UTR Clone

Specifications

Product Data
Product Name	RMND5B (NM_022762) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	GID2; GID2B
ACCN	NM_022762
Insert Size	2000 bp
Sequence Data	Insert Sequence (showhide) >SC206249 3’UTR clone of NM_022762 The sequence shown below is from the reference sequence of NM_022762. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCGGCAGATGGGAAACGCATCATATTCTGATTCCTACCTGGAAGGAATTTTGTTGAAAGGGGTTTTCAC CTGTGAGCCTTGGTCTGTCTCGGTAGGGTGGTCAACTTCAGTGGACTGTGGTTGGTTTCAGAGCGCCTG GCTGAGGAGTTCCACTGAGGGGAGCACTGGAGCAGCCCTTTGGCAGAGGCTGAGGAGGGAGATGGACCA GCCCACGCCTGGCACCTGGCTCCATGGCATAAGGAAAGGGAGATGCTGGCCTCTGTGCTCCTGCTGTCT TTTCCTGTTTCTGTTTGCGTTTGACTTAGTAGCAACCGACAGAGTGGCAAGGGATTTGGTCTTCAGCAG TAGACATCCTTCCACCCCTGCCCTCAGCCAAGTCTCTTGCTGCCATGCCAATGCTATGTCCACCCTTGC CCCTCGGCCCAAGAGTGTCCAGCGGTGGCCCACCTCTTCCTCCCACTACAGCCTCAACAGTATGTACCA TCTCCCACTGTAAATAGTCCCAGTTAGAACGGAATGCCGTTGTTTTATAACTTTGAACAAATGTATTTA CTGCCCTTCTCATTTCTCCTGGCCAACCTTTAGCCTCACTGACAAATTATGACCACATGTCTACCACAC ACAGGGACTGGGCACGGCCTGGTGGCTGCCGCAAACAAAAACATGGCCAGCAGGTATCCAGTGTCCAGG CAGGAAGAACACAACTTGCATCCCTGACTGCGGGGAGCTTAGATGTCAGACCCCGGGCAAGGTGCTTTT ACATATACCCATACCAGATCTTACTAACTCCATAGGAGAAATCCGTGTAATGGGATTCAGGAAAATGAA GTAACTTGCACAACAGGGCTCACAGCTTAGAAAGGAGAGAGCTTGGAGTTTTAACCAGATCTGACCCTC AAGCCCAAGCTATTTCCAGTTTATTCCAGGGTGCCTGAACTTGGCTGTTATGTATACTGAGTCCTGTGC AGGGCCTCTGACAGCAGGAAGGGGCCCCAAGTCTAAAATACTTGAAGGGATTGGGTTACTAGGGCCATT ATGTTAAGCAAGAGAGCTCGGGGGAATGCATTTTAGCTTCATATTCCTATTTAAAATGTGCTGTGTGGG TGGGTAAATTGCTTCCATAAGCTTCACAGTGGCATTTAAGGCTCCTGGGTTAAGTTAGGAATGGGGGTG TTCCTGATGTGGGGGCTTTAGGCTTCCATGAAGTGGGTCTGGGCCCCCTGCCTTACCTCACAGCCCCCA TCTACCCTGGAAGAGGGAGTTGAAAATGCTGGGATAGCAGCAGGATCAGTTCTCAGCTTGAGCCAAAGC ACCCGGCCCTGGGCAGCTGAGCATCAGCACAGAACCCTCTGAGTCCTTTGGGCTCTCTGCTGAGGAAGA CTGCTTCACTCTTCCCGCCCACCAACTCGCTGGCCCAACCAGCAGCTGCTGCTTAAGAAAACACCCACA GACTCACCACATTTTAGTCTTAGCATTTACTTTCCCCACCCCACATTCTTGGAACAGCCTTTAGTTCTA CAGGAAATGGCACTGATGGACAGAAGACTAGCATTACCTTCATGAAAGGGCTGTTAGAGCTGCCTGGGA AGAAGGCGTGCCTTGGGGAACTGGGAAGATGCCGTCAGTGTGGGTGGGCAGGAGGACAGCCAGTCGTCC TGCTGCCAGCCCAATAGCTTCCAGCGGCAGGTGCCCAGGTGCTACCGGAGCCCCTCATAGGGGTAGGGG CAGGGACTGCACCTCCTCCAGGCACTCATCGTAAGCCTCCTGGTACTCCTCATGGGGCTTGACCATTAT CACACAGGTGGGGCGCTTGGAGCCTGCGGCTGCACCCAGGTCCTACAGAGGGGAAAGAAGTGCTGTTTG GAAAAAAGCTGTACAACCTGTATGCCAGGAAGTCACCAACTGATGACCCACCAGCCTAATCTGGCCCAC AACCATGTTCTGTTCGGTCCATGTTCTATTTAAAAGCATCTTGAATTGGTTGCCATCATTTAAACTCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_022762.5
Synonyms	GID2; GID2B
Summary	Core component of the CTLH E3 ubiquitin-protein ligase complex that selectively accepts ubiquitin from UBE2H and mediates ubiquitination and subsequent proteasomal degradation of the transcription factor HBP1. MAEA and RMND5A are both required for catalytic activity of the CTLH E3 ubiquitin-protein ligase complex (PubMed:29911972). Catalytic activity of the complex is required for normal cell proliferation (PubMed:29911972). The CTLH E3 ubiquitin-protein ligase complex is not required for the degradation of enzymes involved in gluconeogenesis, such as FBP1 (PubMed:29911972).[UniProtKB/Swiss-Prot Function]
Locus ID	64777
MW	73.9

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