BCAR3 (NM_003567) Human 3' UTR Clone

Specifications

Product Data
Product Name	BCAR3 (NM_003567) Human 3' UTR Clone
Vector	pMirTarget
Synonyms	AND-34; MIG7; NSP2; SH2D3B
ACCN	NM_003567
Insert Size	530 bp
Sequence Data	Insert Sequence (showhide) >SC206246 3’UTR clone of NM_003567 The sequence shown below is from the reference sequence of NM_003567. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC CCTCCTCCTGTAAAGCAGGCAGAGCTTTGATAACTCTCCAGAGAACCTTTAGAATATCTTTTCAAGTTT CCCCAGCTTCATCTTTGGGAAAGCTTACTGTTTTTGATAAAGTAATAATGTGCAAATCTGACAATATAC AAGCTTTTAGTATCCACAGGATATTAAACGTGTAAATTGCACAGAGCACACTTATTTATGAATTGTCTA AAGTTACTACTGATTTTAAAATGAATAATTTATTATTAAGGTAACTACTGCTAATGTTGATCAGCAAAT TTAAGAGAAGACCTAGCTATGTTGGCTGGTTGCTTTCTATTATCATGGTATTTGACCATTTTAGTTTTA ATTCCATGTCAGATAAGTGTAAATAGAAGAGTTTAAAAGCATGAAACATTTCAGAAGGTATCAGTTATA TGATATTCTTTAAACAAATATGAAAAATGTAAATACTCATGAATGAAAATACATCTTTTTGTGAAACAG TTGTATCCAGTCTCTTTCATATTAAACAACTCATCTTGGTACAATAA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG
Restriction Sites	SgfI-MluI
OTI Disclaimer	Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs).
Reference Data
RefSeq	NM_003567.4
Synonyms	AND-34; MIG7; NSP2; SH2D3B
Summary	Breast tumors are initially dependent on estrogens for growth and progression and can be inhibited by anti-estrogens such as tamoxifen. However, breast cancers progress to become anti-estrogen resistant. Breast cancer anti-estrogen resistance gene 3 was identified in the search for genes involved in the development of estrogen resistance. The gene encodes a component of intracellular signal transduction that causes estrogen-independent proliferation in human breast cancer cells. The protein contains a putative src homology 2 (SH2) domain, a hall mark of cellular tyrosine kinase signaling molecules, and is partly homologous to the cell division cycle protein CDC48. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, May 2012]
Locus ID	8412
MW	20.8

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