PML Protein (PML) (NM_033239) Human 3' UTR Clone
CAT#: SC206185
3' UTR clone of promyelocytic leukemia (PML) transcript variant 9 for miRNA target validation
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CNY 4,845.00
货期*
3周
规格
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经常一起买 (2)
Specifications
Product Data | |
Product Name | PML Protein (PML) (NM_033239) Human 3' UTR Clone |
Vector | pMirTarget |
Synonyms | MYL; PP8675; RNF71; TRIM19 |
ACCN | NM_033239 |
Insert Size | 473 bp |
Sequence Data |
>SC206185 3’UTR clone of NM_033239
The sequence shown below is from the reference sequence of NM_033239. The complete sequence of this clone may contain minor differences, such as SNPs. Blue=Stop Codon Red=Cloning site GGCAAGTTGGACGCCCGCAAGATCCGCGAGATTCTCATTAAGGCCAAGAAGGGCGGAAAGATCGCCGTG TAACAATTGGCAGAGCTCAGAATTCAAGCGATCGCC GTCCCAGGCGCCCGTCAAGCAGGCCTCTGAGAGTGCTACCCTTCTCTTGTAACCTTGCAGCCAACACCC CTGCCCGGCCCCTGAGCTGCCTCCTCCAGCCCATGCTCTTACAGGCCCTGCACAGAGTAGCACTCATTA ATTCTTGGTTAAGGAATGAATCAACGAATGAATGGCTATGCATGGACCTCTGGGCAGGGAGACCTGGGT CTTCTCTGGCTGAGAGGGGAAGGCTAAGGCATGGCTGAGATTCAAGCCACCATTCCAGGCCTCTTTGCC CAAGAAAGAAACTTCTGTCACCCTTGCACTCTCCTGTATTCTGAGTCCCTGGCCAATAGCACAGCCTTC CATGCCCCGACCCCCACCCCAAGCCTCTCCACTAGGCCTCTGCCAGGATCTAAGCCCATGAGCACAGGG ACTGGCTATCCCAAGACCTGGCAGATGTGGCTGCTCAATAAACACTTGTTGAACCATCA ACGCGTAAGCGGCCGCGGCATCTAGATTCGAAGAAAATGACCGACCAAGCGACGCCCAACCTGCCATCA CGAGATTTCGATTCCACCGCCGCCTTCTATGAAAGG |
Restriction Sites | SgfI-MluI |
OTI Disclaimer | Our molecular clone sequence data has been matched to the sequence identifier above as a point of reference. Note that the complete sequence of this clone is largely the same as the reference sequence but may contain minor differences , e.g., single nucleotide polymorphisms (SNPs). |
Reference Data | |
RefSeq | NM_033239.3 |
Synonyms | MYL; PP8675; RNF71; TRIM19 |
Summary | The protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This phosphoprotein localizes to nuclear bodies where it functions as a transcription factor and tumor suppressor. Its expression is cell-cycle related and it regulates the p53 response to oncogenic signals. The gene is often involved in the translocation with the retinoic acid receptor alpha gene associated with acute promyelocytic leukemia (APL). Extensive alternative splicing of this gene results in several variations of the protein's central and C-terminal regions; all variants encode the same N-terminus. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008] |
Locus ID | 5371 |
MW | 16.9 |
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